Results 51 to 60 of about 534,870 (272)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Dynamical theory for adaptive systems

Journal of Statistical Mechanics: Theory and Experiment
Abstract The study of adaptive dynamics, involving many degrees of freedom on two separated timescales, one for fast changes of state variables and another for the slow adaptation of parameters controlling the former’s dynamics is crucial for understanding feedback mechanisms underlying evolution and learning.
Pham, Tuan Minh, Kaneko, Kunihiko
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Geometric Hamilton-Jacobi Theory for Nonholonomic Dynamical Systems

, 2009
The geometric formulation of Hamilton--Jacobi theory for systems with nonholonomic constraints is developed, following the ideas of the authors in previous papers.
Abraham R., Bloch A. M., Cortés J., EDUARDO MARTÍNEZ, GIUSEPPE MARMO, Ibort A., JOSÉ F. CARIÑENA, MIGUEL C. MUÑOZ-LECANDA, NARCISO ROMÁN-ROY, Rosenberg R., Vershik A. M., XAVIER GRÀCIA   +11 more
core   +1 more source

Information Theory and Dynamical System Predictability [PDF]

Entropy, 2011
Predicting the future state of a turbulent dynamical system such as the atmosphere has been recognized for several decades to be an essentially statistical undertaking. Uncertainties from a variety of sources are magnified by dynamical mechanisms and given sufficient time, compromise any prediction.
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

First-order dynamical phase transition in models of glasses: an approach based on ensembles of histories

, 2009
We investigate the dynamics of kinetically constrained models of glass formers by analysing the statistics of trajectories of the dynamics, or histories, using large deviation function methods. We show that, in general, these models exhibit a first-order
Binder K, Doi M, Donsker M D, Estelle Pitard, Franz S, Frédéric van Wijland, Gaspard P, Götze W, Jack R, Juan P Garrahan, Jäckle J, Kristina van Duijvendijk, Krönig A, Kubo R, Kurchan J, Kurchan J, Lecomte V, Lecomte V, Maes C, Maes C, Ritort F, Robert L Jack, Ruelle D, Tarjus G, Touchette H, Vivien Lecomte, Zinn-Justin J   +26 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Chaotic Dynamics in Asymmetric Rock-Paper-Scissors Games

IEEE Access, 2019
Evolutionary game dynamics is a combination of game theory and dynamical systems. Using dynamical theory, we investigate chaotic behavior in asymmetric Rock-Paper-Scissors games under imitative dynamics with two different populations.
Wenjun Hu, Gang Zhang, Haiyan Tian, Zhiwei Wang   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source