Results 81 to 90 of about 9,416,898 (346)

Supramolecular dynamics

Chem. Soc. Rev., 2014
Supramolecular systems are reversible and their dynamics is an inherent and essential property. The conceptual framework for kinetic studies of these systems is presented with a focus on the considerations required for experimental design. Selected examples for guest binding to cyclodextrins, cucurbit[n]urils, DNA, serum albumins and bile salt ...
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

CONTINUOUS OPINIONS AND DISCRETE ACTIONS IN OPINION DYNAMICS PROBLEMS [PDF]

, 2008
ANDRÉ C. R. MARTINS
openalex   +1 more source

Exciton dynamics of a fused ring π-conjugated nonfullerene molecule based on dithienonaphthobisthiadiazole [PDF]

, 2023
Yuki Sato, Tsubasa Mikie, Hiroya Yamada, Itaru Osaka, Hideo Ohkita   +4 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Retracted: Analysis of Psychological and Emotional Tendency Based on Brain Functional Imaging and Deep Learning

Discrete Dynamics in Nature and Society, 2023
Discrete Dynamics in Nature and Society
doaj   +1 more source

Evolutionary dynamics of language systems [PDF]

, 2017
Simon J. Greenhill, Chieh‐Hsi Wu, Xia Hua, Michael Dunn, Stephen C. Levinson, Russell D. Gray   +5 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Retracted: Research on Human Motion Analysis in Moving Scene Based on Timing Detection and Video Description Algorithm

Discrete Dynamics in Nature and Society, 2023
Discrete Dynamics in Nature and Society
doaj   +1 more source