Results 211 to 220 of about 18,529 (254)

Kappa-opioid receptor stimulation in the nucleus accumbens shell and ethanol drinking: Differential effects by rostro-caudal location and level of drinking. [PDF]

open access: yesNeuropsychopharmacology
Pirino BE   +7 more
europepmc   +1 more source

Nonopiate Effects of Dynorphin and Des-Tyr-Dynorphin [PDF]

open access: possibleScience, 1982
Intracerebroventricular administration of dynorphin produced potent and long-lasting effects on motor function and the electroencephalogram in rats. In addition, local iontophoretic or pressure ejection of dynorphin consistently inhibited hippocampal unit activity.
Giulio Baldrighi   +4 more
openaire   +2 more sources
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DYNORPHIN AND EPILEPSY

Progress in Neurobiology, 1996
Studies on dynorphin involvement in epilepsy are summarised in this review. Electrophysiological, biochemical and pharmacological data support the hypothesis that dynorphin is implicated in specific types of seizures. There is clear evidence that this is true for complex partial (limbic) seizures, i.e.
Simonato M., Romualdi P.
openaire   +3 more sources

Pharmacology of Dynorphin

Annual Review of Pharmacology and Toxicology, 1988
Like other opioids, the dynorphins play a role in wide variety of physiological parameters, including pain regulation, motor activity, cardiovascular regulation, respiration, temperature regulation, feeding behavior, hormone balance, and the response to shock or stress. The dynorphins are unusual if not unique, however, in that they frequently modulate
Andrew P. Smith, Nancy M. Lee
openaire   +3 more sources

Rimorphin (dynorphin B) exists together with α-neo-endorphin and dynorphin (dynorphin A) in human hypothalamus

Biochemical and Biophysical Research Communications, 1983
Rimorphin (dynorphin B) has been demonstrated to exist together with alpha-neo-endorphin and dynorphin(1-17) (dynorphin A) in the human hypothalamus. The content of rimorphin was comparable to that of alpha-neo-endorphin and somewhat higher than that of dynorphin. This result is quite similar to the recent observations in bovine, porcine and rat neural
Hiroo Imura   +6 more
openaire   +3 more sources

Conversion of Leumorphin (Dynorphin B‐29) to Dynorphin B and Dynorphin B‐14 by Thiol Protease Activity

Journal of Neurochemistry, 1986
AbstractDynorphin B (rimorphin) is formed from leumorphin (dynorphin B‐29) by the action of a thiol protease from rat brain membranes, in a single step. This represents a “single‐arginine cleavage” between threonine‐13 and arginine‐14 of the substrate. We have observed that in addition to dynorphin B, dynorphin B‐14 is formed from dynorphin B‐29. Among
Avram Goldstein, Lakshmi A. Devi
openaire   +3 more sources

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