Results 111 to 120 of about 22,550,361 (272)

Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors [PDF]

open access: yes, 2017
To investigate the role of A2A adenosine receptors in adaptive responses to chronic intermittent dopamine receptor stimulation, we compared the behavioral sensitization elicited by repeated L-DOPA treatment in hemiparkinsonian wild-type (WT) and A2A ...
Chen, J.-F.   +8 more
core   +1 more source

Purification and Biochemical Characterization of TsMS 3 and TsMS 4: Neuropeptide-Degrading Metallopeptidases in the Tityus serrulatus Venom

open access: yesToxins, 2019
Although omics studies have indicated presence of proteases on the Tityus serrulatus venom (TsV), little is known about the function of these molecules.
Daniela Cajado-Carvalho   +7 more
doaj   +1 more source

The degradation of dynorphin A in brain tissue in vivo and in vitro [PDF]

open access: green, 1987
Elizabeth A. Young   +3 more
openalex   +1 more source

Stress rapidly suppresses in vivo LH pulses and increases activation of RFRP-3 neurons in male mice [PDF]

open access: yes, 2018
Restraint stress is a psychosocial stressor that suppresses reproductive status, including LH pulsatile secretion, but the neuroendocrine mechanisms underlying this inhibition remains unclear.
Hughes, Jessica K   +4 more
core   +1 more source

A genetic polymorphism of the endogenous opioid dynorphin modulates monetary reward anticipation in the corticostriatal loop.

open access: yesPLoS ONE, 2014
The dynorphin/κ-opioid receptor (KOP-R) system has been shown to play a role in different types of behavior regulation, including reward-related behavior and drug craving.
Mikhail Votinov   +9 more
doaj   +1 more source

[3H]dynorphin a binding and κ selectivity of prodynorphin peptides in rat, guinea-pig and monkey brain [PDF]

open access: green, 1986
Elizabeth A. Young   +5 more
openalex   +1 more source

Imaging mass spectrometry reveals elevated nigral levels of dynorphin neuropeptides in L-DOPA-induced dyskinesia in rat model of Parkinson's disease.

open access: yesPLoS ONE, 2011
L-DOPA-induced dyskinesia is a troublesome complication of L-DOPA pharmacotherapy of Parkinson's disease and has been associated with disturbed brain opioid transmission.
Anna Ljungdahl   +4 more
doaj   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

open access: yes, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source

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