Results 91 to 100 of about 120,854,643 (210)
Calcium influx into phospholipid vesicles caused by dynorphin neuropeptides
, 2008 Dynorphins, endogeneous opioid peptides, function as ligands to the opioid kappa receptors but also induce non-opioid excitotoxic effects. Dynorphin A can increase the intra-neuronal calcium concentration through a non-opioid and non-NMDA mechanism.
Hugonin, L +10 more
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, 1994 The granule cell population response to perforant path stimulation decreased significantly within seconds following release of endogenous dynorphin from dentate granule cells.
CT Drake +6 more
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The mechanism of action for the block of NMDA receptor channels by the opioid peptide dynorphin
, 1995 Dynorphin is one of the endogenous opioids that modulates the excitability of nociceptive (pain-sensing) neurons. We have shown recently that dynorphin blocks NMDA-activated currents directly without the participation of kappa-opioid receptors.
L Chen, LY Huang, Y Gu
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Clinical trial of electroacupuncture at Neimadian-point for cancer pain
针刺研究, 2020 Objective To observe the clinical efficacy and safety of electroacupuncture(EA) at Neimadian-point for cancer pain. Methods A total of 140 cancer patients with pain were randomly divided into EA and control groups, with 70 cases in each group.
HAN Xue-chang +6 more
doaj
Dynorphin binds to neuropeptide Y and peptide YY receptors in human neuroblastoma cell lines
, 1994 The modulation of neuropeptide Y (NPY) and peptide YY (PYY) receptors by dynorphin, luteinizing hormone-releasing hormone (LHRH), corticotropin-releasing factor (CRF), and cholecystokinin octapeptide has been studied in human neuroblastoma cell lines SK-
K. Sano +10 more
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Nature CommunicationsThe hippocampus is pivotal in integrating emotional processing, learning, memory, and reward-related behaviors. The dorsal hippocampus (dHPC) is particularly crucial for episodic, spatial, and associative memory, and has been shown to be necessary for ...
Khairunisa Mohamad Ibrahim +15 more
doaj +1 more source
Neurobiology of StressA major challenge for the treatment of alcohol use disorder (AUD) is relapse to alcohol use, even after protracted periods of self-imposed abstinence. Stress significantly contributes to the chronic relapsing nature of AUD, given its long-lasting ability
Francisco J. Flores-Ramirez +2 more
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针刺研究, 1999 It was observed the effects of intracerebroventricular (i. c. v. ) injection of naloxone and anti- opi- oid peptide sera on the analgesia and the enhancement of electroacupuncture (EA ) analgesia caused by somatostatin (SS) in this study. Injection(i. c.
刘玲爱 +5 more
doaj +2 more sources
Spinal astrocytes produce and secrete dynorphin neuropeptides
, 2013 a b s t r a c t Dynorphin peptide neurotransmitters (neuropeptides) have been implicated in spinal pain processing based on the observations that intrathecal delivery of dynorphin results in proalgesic effects and disruption of extracellular dynorphin ...
Vivian Hook +4 more
core
A computer simulation of dynorphin A (1-17) induced spinal cord injury.
, 1997 A computer simulation of dynorphin A (1-17) induced spinal cord ...
Pankaj Mohan. Saxena (7970870)
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