Results 111 to 120 of about 16,204 (223)

A gas-liquid solid phase peptide and protein sequenator [PDF]

, 1981
A new miniaturized protein and peptide sequenator has been constructed which uses gas phase reagents at the coupling and cleavage steps of the Edman degradation. The sample is embedded in a matrix of Polybrene dried onto a porous glass fiber disc located
Dreyer, William J., Hewick, Rodney M., Hood, Leroy E., Hunkapiller, Michael W.   +3 more
core  

Interaction between corticotropin-releasing factor, orexin, and dynorphin in the infralimbic cortex may mediate exacerbated alcohol-seeking behavior

Neurobiology of Stress
A major challenge for the treatment of alcohol use disorder (AUD) is relapse to alcohol use, even after protracted periods of self-imposed abstinence. Stress significantly contributes to the chronic relapsing nature of AUD, given its long-lasting ability
Francisco J. Flores-Ramirez, Jessica M. Illenberger, Rémi Martin-Fardon   +2 more
doaj   +1 more source

Dorsal hippocampus to nucleus accumbens projections drive reinforcement via activation of accumbal dynorphin neurons

Nature Communications
The hippocampus is pivotal in integrating emotional processing, learning, memory, and reward-related behaviors. The dorsal hippocampus (dHPC) is particularly crucial for episodic, spatial, and associative memory, and has been shown to be necessary for ...
Khairunisa Mohamad Ibrahim, Nicolas Massaly, Hye-Jean Yoon, Rossana Sandoval, Allie J. Widman, Robert J. Heuermann, Sidney Williams, William Post, Sulan Pathiranage, Tania Lintz, Azra Zec, Ashley Park, Waylin Yu, Thomas L. Kash, Robert W. Gereau, Jose A. Morón   +15 more
doaj   +1 more source

Kappa opioid receptor control of motivated behavior revisited. [PDF]

Neuropsychopharmacology
Farahbakhsh ZZ, Siciliano CA.
europepmc   +1 more source

Multifaceted modulation of human opioid receptors by kratom alkaloids: binding affinity, functional selectivity, and allosteric activity. [PDF]

Front Pharmacol
Hemby SE, Rangel-Grimaldo M, McIntosh S, Zheng J, Flores-Bocanegra L, Graf TN, Coover RA, Oberlies NH.   +7 more
europepmc   +1 more source

Discovery of a pyridine-piperazine-based small molecule that enhances the activity of peptidase neurolysin. [PDF]

J Pharmacol Exp Ther
ElSayed ElZorkany H, Kandil H, Jayaraman S, Aly A, Esfahani SH, Patel D, Dannecker D, Maciag M, Paul A, Lowran K, Kumari S, Bose S, Ostrov DA, Wu CG, Dickson A, Abbruscato TJ, Trippier PC, Orlando BJ, Karamyan VT.   +18 more
europepmc   +1 more source

Dynorphin Deficiency in Tourette's Syndrome [PDF]

International Journal of Neuroscience, 1989
openaire   +2 more sources

Kappa Opioid Receptors Control a Stress-Sensitive Brain Circuit and Drive Cocaine Seeking. [PDF]

J Neurosci
Martinez Damonte V, Bailey LG, Thakar A, Stralka J, Brown TE, Kauer JA.   +5 more
europepmc   +1 more source

Opioids regulate the functional state of immune cells and reduce inflammatory cardiac injury: Role of opioid receptors, MRGPRX2, and TLR4. [PDF]

J Biomed Res
Gusakova SV, Sirotina M, Maslov LN, Slidnevskaya AS, Kilin M, Kurbatov BK, Kan A, Derkachev IA, Fu F.   +8 more
europepmc   +1 more source

Dysregulated Plasticity in Serotonin, Galanin, and Opioid Systems Contributes to Limbic Seizure Recruitment in Wistar Audiogenic Rat. [PDF]

J Neurochem
Camilo TA, Valentim-Lima E, de Oliveira JAC, Garcia-Cairasco N, Reis LC, Nani JV, Mecawi AS.   +6 more
europepmc   +1 more source