Results 81 to 90 of about 120,854,643 (210)

Altered expression of kisspeptin, dynorphin, and related neuropeptides in polycystic ovary syndrome: A cross-sectional study

International Journal of Reproductive BioMedicine
Background: Since kisspeptin (KISS1) in the hypothalamus is affected by the inhibitory effect of dynorphin, it raises questions about the controlled balance of these 2 neuropeptides in women with and without polycystic ovary syndrome (PCOS).
Andon Hestiantoro, Rachellina Noor Al Maghfira, Ratna Fathmasari, Ririn Rahmala Febri, Ericko Ongko Joyo, Raden Muharam, Gita Pratama, Anom Bowolaksono   +7 more
doaj   +1 more source

Microiontophoretic Application of Dynorphin in Dental Pain: Excitatory or Inhibitory Effects

Journal of Pain Research
Seung-Ho Choi,* Yu-Mi Kim,* Jo-Young Son, Dong-Kuk Ahn Department of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu, Korea*These authors contributed equally to this workCorrespondence: Dong-Kuk Ahn, Department of ...
Choi SH, Kim YM, Son JY, Ahn DK
doaj  

Malnutrition alters protein expression of KNDy neuropeptides in the arcuate nucleus of mature ewes

Frontiers in Physiology
The neuropeptides kisspeptin, neurokinin B, and dynorphin A are imperative for the pulsatile secretion of gonadotropin-releasing hormone and luteinizing hormone to ultimately regulate reproductive cyclicity.
Jennifer F. Thorson, Ligia D. Prezotto
doaj   +1 more source

[3H]dynorphin a binding and [kappa] selectivity of prodynorphin peptides in rat, guinea-pig and monkey brain [PDF]

, 1986
We have previously demonstrated that [3H]dynorphin A selectively labels [kappa] opioid receptors in guinea-pig whole brain. In these current studies, using protection from inactivation by [beta]-chloronaltrexamine ([beta]-CNA), we are able to demonstrate
Walker, J. Michael, Young, Elizabeth A., Lewis, Michael E., Houghten, Richard A., Akil, Huda, Woods, James H.   +5 more
core   +1 more source

Structural basis of divergent substrate recognition and inhibition of human neurolysin

Scientific Reports
A zinc metallopeptidase neurolysin (Nln) processes diverse bioactive peptides to regulate signaling in the mammalian nervous system. To understand how Nln interacts with various peptides with dissimilar sequences, we determined crystal structures of Nln ...
Ke Shi, Sounak Bagchi, Jordis Bickel, Shiva H. Esfahani, Lulu Yin, Tiffany Cheng, Vardan T. Karamyan, Hideki Aihara   +7 more
doaj   +1 more source

Dose-effect relationship between electroacupuncture with different parameters and the regulation of endogenous opioid peptide system

World Journal of Acupuncture - Moxibustion
Endogenous opioid peptides (EOP) are the neurochemical basis of the anesthetic and analgesic effects of acupuncture, and the quantity of acupuncture stimulus can be controlled accurately by using electroacupuncture (EA).
Ping CHEN, Hong XU, Ren ZHANG, Xue-song TIAN   +3 more
doaj   +1 more source

Dynamic Interactions between Orexin and Dynorphin May Delay Onset of Functional Orexin Effects: A Modeling Study

, 2011
Orexin (also known as hypocretin) neurons play a key role in regulating sleep-wake behavior, but the links between orexin neuron electrophysiology and function have not been explored.
Katherine S. Williams, Cecilia G. Diniz Behn   +1 more
core   +1 more source

Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat [PDF]

, 1985
The substantia nigra is among the richest pro-dynorphin terminal field regions in the rat brain. We therefore contrasted processing in this area to the known processing in the posterior pituitary. Fractionation of acid extracts of the posterior pituitary
Dores, Robert M., Lewis, Michael E., Akil, Huda, Khachaturian, Henry, Watson, Stanley J.   +4 more
core   +1 more source

Uma Nova visão da participação dos receptores B1 e B2 para cininas na dor neuropática orofacial [PDF]

, 2011
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011Embora pouco prevalente entre a população, a neuralgia do trigêmeo é uma das condições mais dolorosas.
Luiz, Ana Paula
core  

Exposure to Cocaine Alters Dynorphin-Mediated Regulation of Excitatory Synaptic Transmission in Nucleus Accumbens Neurons

, 2011
Dysregulation of excitatory synaptic input to nucleus accumbens (NAc) medium spiny neurons (MSNs) underlies a key pathophysiology of drug addiction and addiction-associated emotional and motivational alterations.
Peter A. Neumann, Dong, Yan, Yan Dong, Panksepp, Jaak, Oliver M. Schlüter, Schlüter, Oliver M., Ping Mu, Neumann, Peter A., Jaak Panksepp, Mu, Ping   +9 more
core   +1 more source