Results 51 to 60 of about 22,550,361 (272)
PLoS ONE, 2009 Stress is a complex human experience and having both rewarding and aversive motivational properties. The adverse effects of stress are well documented, yet many of underlying mechanisms remain unclear and controversial. Here we report that the anxiogenic
Michael R Bruchas +3 more
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Journal of reproduction and development, 2012 Neurons in the arcuate nucleus (ARC) that concomitantly express kisspeptin, neurokinin B (NKB) and dynorphin A are termed KNDy neurons and are likely candidates for the intrinsic gonadotropin-releasing hormone (GnRH) pulse generator.
Y. Wakabayashi +4 more
semanticscholar +1 more source
Journal of Neuroinflammation, 2022 Background Adverse pathophysiological and behavioral outcomes related to mild traumatic brain injury (mTBI), posttraumatic stress disorder (PTSD), and chronic pain are common following blast exposure and contribute to decreased quality of life, but ...
Suhjung Janet Lee +7 more
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Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]
, 2013 Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Hrabovszky, Erik, Liposits, Zsolt
core +1 more source
Estradiol treatment prevents injury induced enhancement in spinal cord dynorphin expression.
Frontiers in Physiology, 2012 Administration of the ovarian steroid estradiol in male and female animals has been shown to have neuromodulatory and neuroprotective effects in a variety of experimental models. In the present study, spinal tissues from dermatomes just above (T5-7, at
Daya S. Gupta, Charles H. Hubscher
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Role of Neurokinin B and Dynorphin A in pituitary gonadotroph and somatolactotroph cell lines.
Endocrine journal, 2012 The role of Neurokinin B (NKB) and Dynorphin A (Dyn) in the regulation of the hypothalamic pituitary axis is an important area of recent investigation.
T. Mijiddorj +5 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2016 Aconitines, including bulleyaconitine A, probably the most bioactive and abundant alkaloids in Aconitum plant, are a group of diester C19-diterpenoid alkaloids with one acetylester group attached to C8 of the diterpenoid skeleton and one benzoylester ...
Teng-Fei Li, Yong-Xiang Wang, Nian Gong
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Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.
Endocrinology, 2007 Kisspeptin is a potent stimulator of GnRH secretion that has been implicated in the feedback actions of ovarian steroids. In ewes, the majority of hypothalamic kisspeptin neurons are found in the arcuate nucleus (ARC), with a smaller population located ...
R. Goodman +10 more
semanticscholar +1 more source
Membrane leakage induced by dynorphins
FEBS Letters, 2006 Dynorphins, endogeneous opioid peptides, function as ligands to the opioid kappa receptors and induce non‐opioid excitotoxic effects. Here we show that big dynorphin and dynorphin A, but not dynorphin B, cause leakage effects in large unilamellar phospholipid vesicles (LUVs).
Vladana Vukojević +3 more
openaire +3 more sources
Neural Plasticity, 2020 Background. Visceral pain is one of the most common types of pain and particularly in the abdomen is associated with gastrointestinal diseases. Bulleyaconitine A (BAA), isolated from Aconitum bulleyanum, is prescribed in China to treat chronic pain.
Sheng-Nan Huang +5 more
doaj +1 more source