Results 21 to 30 of about 140,996 (352)

Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives

Nature Communications, 2023
Microbiota-gut-brain axis may play an important role in Parkinson’s disease (PD). Here, the authors assess gut microbiota in early PD, REM sleep behaviour disorder (RBD) and first-degree relatives of RBD and show PD-like gut dysbiosis occurs in RBD and ...
Bei Huang, S. Chau, Yaping Liu, J. Chan, Jing Wang, S. Ma, Jihui Zhang, Paul K. S. Chan, Yun Kit Yeoh, Zigui Chen, Li Zhou, S. Wong, Vincent C. T. Mok, K. To, H. Lai, S. Ng, C. Trenkwalder, F. K. Chan, Y. Wing   +18 more
semanticscholar   +1 more source

Emerging role of gut microbiota dysbiosis in neuroinflammation and neurodegeneration

Frontiers in Neurology, 2023
Alzheimer's disease (AD), is a chronic age-related progressive neurodegenerative disorder, characterized by neuroinflammation and extracellular aggregation of Aβ peptide. Alzheimer's affects every 1 in 14 individuals aged 65 years and above.
Riddhi Solanki, A. Karande, Prathibha Ranganathan   +2 more
semanticscholar   +1 more source

Intestinal dysbiosis as an intraoperative predictor of septic complications: evidence from human surgical cohorts and preclinical models of peritoneal sepsis

Scientific Reports, 2023
Major surgery exposes the intestinal microbiota to inflammatory and antibiotic stressors, which alter the microbiota composition of the intestinal lumen and fecal contents.
Daniel Spari, Simone N. Zwicky, Bahtiyar Yilmaz, Lilian Salm, Daniel Candinas, Guido Beldi   +5 more
doaj   +1 more source

Value of conditionally-pathogenic microflora index as predicting factor of bacterial dysbiosis’ development

Journal of Education, Health and Sport, 2020
An article shows the most informative indicators that objectively reflect the condition of the pathological process of dysbiosis, and a system for predicting of the risk of occurrence and severity of dysbiosis according to these indicators is developed ...
O. A. Hruzevskyi
doaj   +1 more source

Dysbiosis: The first hit for digestive system cancer

Frontiers in Physiology, 2022
Gastrointestinal cancer may be associated with dysbiosis, which is characterized by an alteration of the gut microbiota. Understanding the role of gut microbiota in the development of gastrointestinal cancer is useful for cancer prevention and gut ...
Si Mei, Si Mei, Zhe Deng, Zhe Deng, Yating Chen, Yating Chen, Dimin Ning, Dimin Ning, Yinmei Guo, Xingxing Fan, Ruoyu Wang, Ruoyu Wang, Yuelin Meng, Yuelin Meng, Qing Zhou, Xuefei Tian, Xuefei Tian   +16 more
doaj   +1 more source

Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases

Biomedicines, 2022
The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a critical player in gut homeostasis maintenance as it ensures the complex crosstalk between gut microbes (both commensals and pathogens) and the host immune ...
C. Stolfi, C. Maresca, G. Monteleone, F. Laudisi   +3 more
semanticscholar   +1 more source

Intestinal Dysbiosis and Autoimmune Pancreatitis [PDF]

Frontiers in Immunology, 2021
Autoimmune pancreatitis (AIP) is a chronic fibro-inflammatory disorder of the pancreas. Recent clinicopathological analysis revealed that most cases of AIP are pancreatic manifestations of systemic IgG4-related disease (IgG4-RD), a newly established disease characterized by enhanced IgG4 antibody responses and the involvement of multiple organs ...
Tomoe Yoshikawa, Tomohiro Watanabe, Ken Kamata, Akane Hara, Kosuke Minaga, Masatoshi Kudo   +5 more
openaire   +3 more sources

Change in intestinal alkaline phosphatase activity is a hallmark of antibiotic-induced intestinal dysbiosis [PDF]

Animal Bioscience, 2023
Objective Intestinal alkaline phosphatase (IAP) maintains intestinal homeostasis by detoxifying bacterial endotoxins and regulating gut microbiota, and lipid absorption.
Wijesooriya Mudhiyanselage Nadeema Dissanayake, Malavige Romesha Chandanee, Sang-Myeong Lee, Jung Min Heo, Young-Joo Yi   +4 more
doaj   +1 more source

Gut Microbiota Dysbiosis: Triggers, Consequences, Diagnostic and Therapeutic Options

Microorganisms, 2022
The global incidence of numerous immune-mediated, metabolic, neurodegenerative, and psychiatric diseases is steadily increasing [...].
T. Hrncír
semanticscholar   +1 more source

Lupus Nephritis and Dysbiosis

Biomedicines, 2023
Lupus nephritis (LN) is one of the most common and serious complications of systemic lupus erythematosus (SLE). The risk factors for developing LN by SLE patients are not fully understood. They are considered to be a mix of genetic and environmental variables, one of them being dysbiosis, proposed recently to interfere with autoimmunity. As of yet, the
Marta Monticolo, Krzysztof Mucha, Bartosz Foroncewicz   +2 more
openaire   +3 more sources