Results 41 to 50 of about 169,171 (302)

Microbiota-associated immunotherapy resistance caused by deficient PD-L2 - RGMb signaling

OncoImmunology, 2023
In a recent paper in Nature, Park et al. propose a mechanism through which intestinal dysbiosis compromises the efficacy of immunotherapy targeting the PD-L1/PD−1 interaction. Dysbiosis may upregulate a pair of checkpoint molecules, i.e.
Marine Fidelle, Isabelle Lebhar, Laurence Zitvogel, Guido Kroemer   +3 more
doaj   +1 more source

Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models. [PDF]

, 2016
Metabolic syndrome (MetS), characterized as obesity, insulin resistance, and non-alcoholic fatty liver diseases (NAFLD), is associated with vitamin D insufficiency/deficiency in epidemiological studies, while the underlying mechanism is poorly addressed.
Cai, Linbi, Chen, Zishuo, Duan, Zhongping, Han, Yuan-Ping, Hu, Richard, Lai, Yuchen, Liu, Zhenqui, Lugea, Aurelia, Luo, Mei, Nie, Yuanyang, Pandol, Stephen J, Su, Danmei, Sun, Qun, Tsukamoto, Hidekazu, Wu, Guihui, Wu, Pengfei, Xiao, Zhixiong, Zhang, Li, Zheng, Sujun, Zhu, Airu   +19 more
core   +2 more sources

Analysis of the Relationship Between the Degree of Dysbiosis in Gut Microbiota and Prognosis at Different Stages of Primary Hepatocellular Carcinoma

Frontiers in Microbiology, 2019
Gut microbiota dysbiosis is closely associated with primary hepatocellular carcinoma (HCC). Recent studies have evaluated the early diagnosis of primary HCC through analysis of gut microbiota dysbiosis.
Jiajia Ni, Jiajia Ni, Rong Huang, Huifang Zhou, Xiaoping Xu, Xiaoping Xu, Yang Li, Yang Li, Peihua Cao, Peihua Cao, Kebo Zhong, Kebo Zhong, Mei Ge, Mei Ge, Xiaoxia Chen, Xiaoxia Chen, Baohua Hou, Min Yu, Baogang Peng, Qiao Li, Peng Zhang, Yi Gao, Yi Gao   +22 more
doaj   +1 more source

Intestinal Dysbiosis and the Developing Lung: The Role of Toll-Like Receptor 4 in the Gut-Lung Axis. [PDF]

, 2020
BackgroundIn extremely premature infants, postnatal growth restriction (PNGR) is common and increases the risk of developing bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH). Mechanisms by which poor nutrition impacts lung development are
Chiamvimonvat, Nipavan, Gerard, Kimberly, Halloran, Katrina, Hanhauser, Ashley, Lakshminrusimha, Satyan, Monacelli, Sveva, Steinhorn, Robin H, Thai, Phung N, Underwood, Mark A, Warford, Cris, Wedgwood, Stephen   +10 more
core  

Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts. [PDF]

, 2017
ObjectiveTo compare faecal microbial composition in patients with systemic sclerosis (SSc) from 2 independent cohorts with controls and to determine whether certain genera are associated with SSc-gastrointestinal tract (GIT) symptoms.DesignAdult patients
Braun, Jonathan, Chang, Lin, Chang, Yu-Ling, Clements, Philip J, Hoffmann-Vold, Anna-Maria, Hov, Johannes R, Jacobs, Jonathan P, Kummen, Martin, Labus, Jennifer S, Lagishetty, Venu, Mayer, Emeran A, Midtvedt, Øyvind, Molberg, Øyvind, Tillisch, Kirsten, Volkmann, Elizabeth R   +14 more
core   +1 more source

Mucosaprotective action of the phytopreparation "Biotrit" at experimental hepatogenic colitis

Journal of Education, Health and Sport, 2017
Aim: To determine the role of dysbiosis in the development of colitis and to show the therapeutic and preventive effects of the phytopreparation "Biotrit" at this pathology.
A. V. Bocharov
doaj   +3 more sources

Enteric dysbiosis and fecal calprotectin expression in premature infants. [PDF]

, 2019
BackgroundPremature infants often develop enteric dysbiosis with a preponderance of Gammaproteobacteria, which has been related to adverse clinical outcomes.
A Ghidini, AG Roseth, Akhil Maheshwari, Alyson L. Yee, BC MacQueen, Benjamin A. Torres, Bradley Kane, BS Fullerton, C Rouge, C Urbaniak, CJ Stewart, D Boccia, D Canioni, DC Straus, EA Albanna, F Sommer, FJ Verdam, HH Stone, HM Moore, HR Hill, J Penders, Jack A. Gilbert, JM Rhoads, JP Gisbert, LM Kindinger, M Pammi, M Zhang, Maureen W. Groer, MC Lu, MS Goyal, N Gregersen, PD Smith, PJ Turnbaugh, R Cortese, RM Torrazza, RM Torrazza, SH Patel, Thao T. B. Ho, TTB Ho, VK Gupta, Y Wang, Y Zhou   +41 more
core   +2 more sources

Microbial dysbiosis in periodontitis

Journal of Indian Society of Periodontology, 2013
Periodontitis is a biofilm-associated inflammatory disease of the periodontium. This disease appears to have multiple etiologies with microbial factor contributing to initiation of the disease and immunological factor of the host propagating the disease.
Sameera G Nath, Ranjith Raveendran
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Factors affecting dysbiosis of the gut microbiota in the elderly and the progress of interventions in traditional Chinese and Western medicine

Frontiers in Cellular and Infection Microbiology
As the population ages, intestinal health in the elderly has become a key area of concern, with gut microbiota dysbiosis emerging as a significant issue.
Zhi-Jun Zhang, Ru Gao, Yu-Tong Lu, Zhi-Liang Zuo, Zhi-Liang Zuo, Yu-Huan Li, Shan Liu, Si-Yuan Song, Yi Wang, Hongyan Lai   +9 more
doaj   +1 more source