Results 51 to 60 of about 199,474 (298)

Paneth cell α-defensin misfolding correlates with dysbiosis and ileitis in Crohn’s disease model mice

Life Science Alliance, 2020
This study provides novel insight into Crohn’s disease where α-defensin misfolding resulting from excessive ER stress in Paneth cells induces dysbiosis and disease progression.
Yu Shimizu, Kiminori Nakamura, Aki Yoshii, Yuki Yokoi, Mani Kikuchi, Ryuga Shinozaki, Shunta Nakamura, Shuya Ohira, Rina Sugimoto, Tokiyoshi Ayabe   +9 more
doaj   +1 more source

Translational Approaches with Antioxidant Phytochemicals against Alcohol-Mediated Oxidative Stress, Gut Dysbiosis, Intestinal Barrier Dysfunction, and Fatty Liver Disease

Antioxidants, 2021
Emerging data demonstrate the important roles of altered gut microbiomes (dysbiosis) in many disease states in the peripheral tissues and the central nervous system.
Jacob W. Ballway, Byoung-Joon Song
doaj   +1 more source

Sialic acid exacerbates gut dysbiosis-associated mastitis through the microbiota-gut-mammary axis by fueling gut microbiota disruption

Microbiome, 2023
Background Mastitis is one of the most severe diseases in humans and animals, especially on dairy farms. Mounting evidence indicates that gastrointestinal dysbiosis caused by induction of subacute ruminal acidosis (SARA) by high-grain diet consumption ...
Cai-Jun Zhao, Xiao-Yu Hu, Min Qiu, Li-Juan Bao, Ke-Yi Wu, Xiangyue Meng, Yi-Hong Zhao, Lian-Jun Feng, S. Duan, Yu-Hong He, Nai-Sheng Zhang, Yun-He Fu   +11 more
semanticscholar   +1 more source

Severe intestinal dysbiosis is prevalent in primary Sjögren’s syndrome and is associated with systemic disease activity

Arthritis Research & Therapy, 2017
Background Altered microbial composition of the intestine, commonly referred to as dysbiosis, has been associated with several autoimmune diseases including primary Sjögren’s syndrome (pSS).
Thomas Mandl, Jan Marsal, Peter Olsson, Bodil Ohlsson, Kristofer Andréasson   +4 more
doaj   +1 more source

Altered gut microbiota composition with antibiotic treatment impairs functional recovery after traumatic peripheral nerve crush injury in mice: effects of probiotics with butyrate producing bacteria

BMC Research Notes, 2022
Objective Antibiotics (ABX) are widely used for life-threatening infections and also for routine surgical operations. Compelling evidence suggests that ABX-induced alterations of gut microbiota composition, termed dysbiosis, are linked with diverse ...
Andrew Rodenhouse, M. A. Hassan Talukder, Jung Il Lee, Prem Kumar Govindappa, Mary O’Brien, Kristen M. Manto, Kelsey Lloyd, Grant D. Wandling, Justin R. Wright, Jeremy R. Chen See, Samantha L. Anderson, Regina Lamendella, John P. Hegarty, John C. Elfar   +13 more
doaj   +1 more source

Gut microbiota dysbiosis contributes to the development of hypertension

Microbiome, 2017
Recently, the potential role of gut microbiome in metabolic diseases has been revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent cardiovascular diseases worldwide, yet whether gut microbiota dysbiosis participates ...
Jing Li, Fangqing Zhao, Yi-Dan Wang, Jun-Ru Chen, J. Tao, G. Tian, Shouling Wu, Wenbin Liu, Qing-Hua Cui, B. Geng, Wei-Li Zhang, R. Weldon, Kelda Auguste, Lei Yang, Xiao-Yan Liu, Li Chen, Xin-Chun Yang, Bao-Li Zhu, Jun Cai   +18 more
semanticscholar   +1 more source

Dysbiosis-induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation

Cell Host and Microbe, 2020
SUMMARY Secondary bile acids (SBAs) are derived from primary bile acids (PBAs) in a process reliant on biosynthetic capabilities possessed by few microbes.
S. Sinha, Yeneneh Haileselassie, L. Nguyen, C. Tropini, Min Wang, L. Becker, Davis L. Sim, Karolin Jarr, Estelle T. Spear, Gulshan Singh, Hong Namkoong, K. Bittinger, M. Fischbach, J. Sonnenburg, Aida Habtezion   +14 more
semanticscholar   +1 more source

Signatures of dysbiosis in fish microbiomes in the context of aquaculture

Reviews in Aquaculture, 2023
Fish microbiome plays an important role in maintaining host homeostasis, with many bacterial functions directly linked to host fitness. Fish microbiome research is advancing fast, especially in the context of aquaculture where several stressors are known
R. Xavier, R. Severino, S. Silva
semanticscholar   +1 more source

The Role of Lower Airway Dysbiosis in Asthma: Dysbiosis and Asthma [PDF]

, 2017
With the development of culture-independent techniques, numerous studies have demonstrated that the lower airway is not sterile in health and harbors diverse microbial communities.
Jodie L. Simpson, Junying Lu, Chao Zhang, Shiji Wang, Jingtong Zheng, Zhongmin Liu, Guoqiang Wang, Xiaohao Zhang, Lingxin Xiong, Fang Wang, Ruipeng Zheng   +10 more
core   +1 more source

INTESTINAL DYSBIOSIS IN YOUNG CHILDREN; POSSIBILITIES OF ITS CORRECTION [PDF]

, 2016
The problem of intestinal dysbiosis and its correction with the use of preand probiotics remains a subject of on-going debate. Current data on intestinal dysbiosis, its clinical manifestations, the role of the intestinal microbiota in the life of the ...
M. Ju. Stepanyan, E. V. Komarova
core   +1 more source