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PGLYRP4 Enhances Shigella flexneri Virulence by Promoting virF Transcription via the CpxA/R Two-Component System. [PDF]
MicrobiologyopenShigella can use the host's innate immune system to optimize the expression of its virulence factors. The PGLYRP4 protein, a member of the host's innate immune system, increases VirF expression in Shigella by stimulating the CpxA/R TCS, thereby enhancing the expression of the virulence system.
Trirocco R, Prosseda G.
europepmc +2 more sources
Environmental Health and Preventive Medicine, 2021 Background Understanding the association between floods and bacillary dysentery (BD) incidence is necessary for us to assess the health risk of extreme weather events.
Yang Ma +3 more
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High mean water vapour pressure promotes the transmission of bacillary dysentery. [PDF]
PLoS ONE, 2015 Bacillary dysentery is an infectious disease caused by Shigella dysenteriae, which has a seasonal distribution. External environmental factors, including climate, play a significant role in its transmission.
Guo-Zheng Li +5 more
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Socio-economic factors of bacillary dysentery based on spatial correlation analysis in Guangxi Province, China. [PDF]
PLoS ONE, 2014 BACKGROUND: In the past decade, bacillary dysentery was still a big public health problem in China, especially in Guangxi Province, where thousands of severe diarrhea cases occur every year. METHODS: Reported bacillary dysentery cases in Guangxi Province
Chengjing Nie +4 more
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BMC Public Health, 2017 Background Bacillary dysentery is the third leading notifiable disease and remains a major public health concern in China. The Beijing–Tianjin–Hebei urban region is the biggest urban agglomeration in northern China, and it is one of the areas in the ...
Chengdong Xu +3 more
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BMC Infectious Diseases, 2008 Background The effects of climate variations on bacillary dysentery incidence have gained more recent concern. However, the multi-collinearity among meteorological factors affects the accuracy of correlation with bacillary dysentery incidence. Methods As
Guo Junqiao +4 more
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Journal of Infection and Public Health, 2018 Background: We aimed to quantify the impact of few times floods on bacillary dysentery in Zhengzhou during 2005–2009. Methods: The Spearman correlation test was applied first to examine the lagged effects of floods on monthly morbidity of bacillary ...
Xiaowen Hu +5 more
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Mechanisms of bacillary dysentery: lessons learnt from infant rabbits
Gut Microbes, 2020 The bacterial pathogen Shigella flexneri causes more than 250 million cases of bacillary dysentery (blood in stool) every year across the world. This human-specific disease is characterized by profuse bloody diarrhea, dramatic ulceration of the colonic ...
Lauren K. Yum, Hervé Agaisse
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Spatio-temporal analysis of bacillary dysentery in Sichuan province, China, 2011–2019
BMC Infectious Diseases, 2021 Background Bacillary dysentery (BD) is a common infectious disease in China and causes enormous economic burdens. The purpose of this study was to describe the epidemiological characteristics of BD and to identify its possible hot spots and potentially ...
Yao Zhang +5 more
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mSphere, 2020 Shigella flexneri is a major cause of bacillary dysentery in Beijing, China. The genetic features and population structure of locally circulating clones remained unclear. In this study, we sequenced the genomes of 93 S. flexneri isolates from patients in
Lang Yang +8 more
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