Blood, 2021 Abstract Congenital dysfibrinogenemia (CD) is caused by structural changes in fibrinogen that modify its function. Diagnosis is based on discrepancy between decreased fibrinogen activity and normal fibrinogen antigen levels and is confirmed by genetic testing.
Casini, Alessandro +1 more
openaire +3 more sources
A 26-year-old pregnant woman with mild gingival bleeding
Clinical and Experimental Obstetrics & Gynecology, 2020 Congenital dysfibrinogenemia is a genetic coagulopathy that leads to compromised fibrinogen function. This case report describes a 26-year-old pregnant woman at the 38th week of gestation who presented with mild gingival bleeding and constant bruising on
J.Z. Zeng +7 more
doaj +1 more source
Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation [PDF]
, 1985 The blood coagulation system of 66 consecutive patients undergoing consecutive liver transplantations was monitored by thrombelastograph and analytic coagulation profile.
Bontempo, FA +7 more
core +1 more source
Fibrinogen Sevilla, a congenital dysfibrinogenemia characterized by an abnormal monomer aggregation and a defective plasmin lysis [PDF]
, 1989 A dysfibrinogenemia (fibrinogen Sevilla) was detected in a 64-yr-old woman with no previous history of hemorrhagic diathesis or thrombosis. Thrombin and reptilase times were prolonged.
Cuesta, B. (Braulia) +5 more
core +1 more source
Hereditary hypofibrinogenemia: A rare cause of chronic liver disease. [PDF]
JPGN RepAbstract Hypofibrinogenemia is characterized by low levels of fibrinogen with patients commonly presenting asymptomatically. This report discusses a case of hereditary hypofibrinogenemia manifesting as chronic liver disease in a 2‐year‐old male who was evaluated for elevated liver enzymes and skin/soft tissue bleeding.
Caringal H +4 more
europepmc +2 more sources
Influence of Fibrinogen Deficiency on Clot Formation in Flow by Hybrid Model [PDF]
, 2014 International audienceIn this work we develop the 2D model suggested in [32] in order to study the impact of fibrinogen concentration and the fibrin polymer production rate on clot growth in flow.
Bessonov, Nikolai +2 more
core +3 more sources
Interference of Monoclonal Gammopathy with Fibrinogen Assay Producing Spurious Dysfibrinogenemia
TH Open, 2019 Abnormal coagulation properties indicative of a dysfibrinogenemia were found in the plasma of an asymptomatic 65-year-old male. An immunoglobulin k light chain was found to interfere with Fg functional assay and coagulation tests (activated partial ...
Francesca Martini +6 more
doaj +1 more source
Screening method for congenital dysfibrinogenemia using clot waveform analysis with the Clauss method [PDF]
, 2021 ArticleInternational journal of laboratory hematology.
Arai, Nobuo +8 more
core +1 more source
Congenital dysfibrinogenemia: fibrinogen detroit [PDF]
Journal of Clinical Investigation, 1969 A 17 yr old female with a congenital bleeding disorder was found to suffer from dysfibrinogenemia. Whole blood and plasma coagulation times were delayed and thrombelastograms were grossly abnormal. Clottability of plasma fibrinogen by addition of thrombin was not demonstrated during the 30 min test period.
E F, Mammen +3 more
openaire +2 more sources
Procoagulant changes in fibrin clot structure in patients with cirrhosis are associated with oxidative modifications of fibrinogen [PDF]
, 2016 Patients with cirrhosis have hemostatic changes, which may contribute to a risk of thrombosis. This in vitro study compares clot formation and structure between patients and healthy subjects.
Adelmeijer, J +6 more
core +2 more sources