Results 31 to 40 of about 1,945 (206)

Guidelines on fibrinogen assays [PDF]

, 2003
No abstract ...
Becker, Blanco, Blomback, Cambas, Chantarangkul, Chantarangkul, Chitolie, Chitolie, Clauss, Cremer, Cushman, De Cristofaro, De Maat, De Metz, Eliasson, Gaffney, Gordon D. O. Lowe, Hantgan, Haverkate, Hoffmann, Humphries, Ian J. Mackie, Jacobsson, Kitchen, Kluft, Lawrie, Lowe, Lowe, Ludlam, Machin, Mackie, Marder, MDA, MDA, Natelson, NCCLS, Nieuwenhuizen, Oosting, Palareti, Rampling, Ratnoff, Rosenson, Rossi, Samuel J. Machin, Steven Kitchen, Swain, Sweetnam, Sweetnam, Thompson, Van Der Bom, Vermylen, Whicher, World Health Organisation Report   +52 more
core   +1 more source

Acquired dysfibrinogenemia caused by monoclonal production of immunoglobulin λ light chain

Haematologica, 2007
Disorders of fibrinogen are usually caused by genetic mutations that result in low protein levels (hypofibrinogenemia) or an abnormal molecule (dysfibrinogenemia). However, environmental and plasma factors can have an acquired effect on its expression or
A. Dear, S.O. Brennan, M.J. Sheat, JM. Faed, P.M. George   +4 more
doaj   +1 more source

Fibrinogen post-translational modifications are biochemical determinants of fibrin clot properties and interactions. [PDF]

FEBS J
The biochemical and biophysical properties of fibrinogen and fibrin, which is formed during coagulation, are critical for proper hemostatic function. The formation of abnormal fibrin clots has been linked to a prothrombotic phenotype and disease states.
Tenopoulou M.
europepmc   +2 more sources

Diagnostic utility of bleeding assessment tools in congenital fibrinogen deficiencies [PDF]

, 2023
Background: The assessment of clinical history is crucial before referring a patient for further laboratory testing. Bleeding assessment tools (BAT) are developed to standardize clinical evaluation.
Azarkeivan, Azita, Baghaipour, Mohammad Reza, Jazebi, Mohammad, Menegatti, Marzia, Moazezi, Somayeh, Mohsenian, Samin, Palla, Roberta, Peyvandi, Flora, Seidizadeh, Omid   +8 more
core   +1 more source

Analysis of polymorphisms Leiden Factor V G1691A and prothrombin G20210A as risk factors for acute myocardial infarction. [PDF]

, 2011
Thrombotic risk increases in elderly, therefore, the understanding of the genetic predisposition of hypercoagulability could make the difference in the prevention of venous and/or arterial thrombotic events.
Branzi, A, Caldarera, CM, CARUSO, Calogero, FORTE, Giusi Irma, Licastro, F, LIO, Domenico, PALMERI, Marisa, SCOLA, Letizia, VACCARINO, Loredana   +8 more
core   +1 more source

Acquired dysfibrinogenemia: monoclonal λ-type IgA binding to fibrinogen caused lower functional plasma fibrinogen level and abnormal clot formation [PDF]

, 2020
ArticleInternational journal of hematology. 112(1): 96-104.
Arai, Shinpei, Honda, Takayuki, Kamijo, Tomu, Nakazawa, Hideyuki, Okumura, Nobuo, Sugano, Mitsutoshi, Takezawa, Yuka, Uehara, Takeshi, Ynagisawa, Ryu   +8 more
core   +1 more source

Evolutionary Signatures amongst Disease Genes Permit Novel Methods for Gene Prioritization and Construction of Informative Gene-Based Networks [PDF]

, 2015
Genes involved in the same function tend to have similar evolutionary histories, in that their rates of evolution covary over time. This coevolutionary signature, termed Evolutionary Rate Covariation (ERC), is calculated using only gene sequences from a ...
Clark, NL, Priedigkeit, N, Wolfe, N
core   +1 more source

Case Report: Unmasked Inherited Dysfibrinogenemia After Everolimus Therapy

Frontiers in Medicine, 2020
A previously hemostatically asymptomatic patient with common variable hypogammaglobulinemia was given everolimus to prevent growth of her liver. Within several months, the patient developed a severe bleeding disorder.
Alona A. Merkulova, Steven C. Mitchell, Sergei Merkulov, Alisa S. Wolberg, Marguerite Neerman-Arbez, Marguerite Neerman-Arbez, Alvin H. Schmaier, Alvin H. Schmaier   +7 more
doaj   +1 more source

GeneTIER: prioritization of candidate disease genes using tissue-specific gene expression profiles. [PDF]

, 2015
Motivation In attempts to determine the genetic causes of human disease, researchers are often faced with a large number of candidate genes. Linkage studies can point to a genomic region containing hundreds of genes, while the high-throughput sequencing ...
Antanaviciute, A, Bonthron, DT, Carr, IM, Crinnion, LA, Daly, C, Markham, AF, Watson, CM   +6 more
core   +1 more source

Automated screening procedure for the phenotypes of congenital fibrinogen disorders using novel parameters, |min1|c and Ac/|min1|c, obtained from clot waveform analysis using the Clauss method [PDF]

, 2021
ArticleClinica chimica acta.
Arai, Nobuo, Arai, Shinpei, Kaido, Takahiro, Kamijo, Tomu, Okumura, Nobuo, Shinohara, Sho, Sugano, Mitsutosho, Suzuki, Takeshi, Uehara, Takeshi, Yoda, Masahiro   +9 more
core   +1 more source