Results 41 to 50 of about 1,146 (191)

Comparison of different activators of coagulation by turbidity analysis of hereditary dysfibrinogenemia and controls

, 2021
Turbidity analysis is widely used as a quantitative technique in hereditary dysfibrinogenemia. We aimed to compare several coagulation triggers in hereditary dysfibrinogenemia and control plasmas. We included 20 patients with hereditary dysfibrinogenemia,
Christine Mouton, Fiore, Mathieu, Philippe Gautier, Mourey, Guillaume, Marguerite Neerman-Arbez, Mathieu Fiore, Neerman Arbez, Marguerite, Marchi Cappelletti, Rita, Mouton, Christine, Rita Marchi, Valérie Gay, Guillaume Mourey, De Moerloose, Philippe, Philippe De Moerloose, Gay, Valérie, Casini, Alessandro, Alessandro Casini, Gautier, Philippe   +17 more
core   +1 more source

Acquired dysfibrinogenemia caused by monoclonal production of immunoglobulin λ light chain

Haematologica, 2007
Disorders of fibrinogen are usually caused by genetic mutations that result in low protein levels (hypofibrinogenemia) or an abnormal molecule (dysfibrinogenemia). However, environmental and plasma factors can have an acquired effect on its expression or
A. Dear, S.O. Brennan, M.J. Sheat, JM. Faed, P.M. George   +4 more
doaj   +1 more source

Fibrin monomers derived from thrombogenic dysfibrinogenemia, Naples-type variant (BβAla68Thr), showed almost entirely normal polymerization [PDF]

, 2018
ArticleTHROMBOSIS RESEARCH.172:1-3(2018)journal ...
Nagata, Kazuhiro, Taira, Chiaki, Kamijo, Tomu, Arai, Shinpei, Higuchi, Yumiko, Okumura, Nobuo   +5 more
core   +1 more source

Laboratory Diagnosis of Dysfibrinogenemia

Archives of Pathology & Laboratory Medicine, 2002
Abstract Dysfibrinogenemia is a coagulation disorder caused by a variety of structural abnormalities in the fibrinogen molecule that result in abnormal fibrinogen function. It can be inherited or acquired. The inherited form is associated with increased risk of bleeding, thrombosis, or both in the same patient or family. Traditionally,
Mark T, Cunningham, John T, Brandt, Michael, Laposata, John D, Olson   +3 more
openaire   +2 more sources

Hereditary hypofibrinogenemia: A rare cause of chronic liver disease. [PDF]

JPGN Rep
Abstract Hypofibrinogenemia is characterized by low levels of fibrinogen with patients commonly presenting asymptomatically. This report discusses a case of hereditary hypofibrinogenemia manifesting as chronic liver disease in a 2‐year‐old male who was evaluated for elevated liver enzymes and skin/soft tissue bleeding.
Caringal H, Maloney N, Mehta K, Jain A, Parashette K.   +4 more
europepmc   +2 more sources

Dysfibrinogenemia and Thrombosis

Archives of Pathology & Laboratory Medicine, 2002
Abstract Objectives.—To review the state of the art relating to congenital dysfibrinogenemia as a potential risk factor for thrombosis, as reflected by the medical literature and the consensus opinion of recognized experts in the field, and to make recommendations for the use of laboratory assays for assessing this thrombotic risk in ...
openaire   +2 more sources

Congenital dysfibrinogenemia: fibrinogen detroit [PDF]

Journal of Clinical Investigation, 1969
A 17 yr old female with a congenital bleeding disorder was found to suffer from dysfibrinogenemia. Whole blood and plasma coagulation times were delayed and thrombelastograms were grossly abnormal. Clottability of plasma fibrinogen by addition of thrombin was not demonstrated during the 30 min test period.
E F, Mammen, A S, Prasad, M I, Barnhart, C C, Au   +3 more
openaire   +2 more sources

Acquired dysfibrinogenemia: monoclonal λ-type IgA binding to fibrinogen caused lower functional plasma fibrinogen level and abnormal clot formation [PDF]

, 2020
ArticleInternational journal of hematology. 112(1): 96-104.
Takezawa, Yuka, Nakazawa, Hideyuki, Kamijo, Tomu, Arai, Shinpei, Ynagisawa, Ryu, Sugano, Mitsutoshi, Honda, Takayuki, Okumura, Nobuo, Uehara, Takeshi   +8 more
core   +1 more source

Congenital Afibrinogenemia and Hypofibrinogenemia: Laboratory and Genetic Testing in Rare Bleeding Disorders with Life-Threatening Clinical Manifestations and Challenging Management

Diagnostics, 2021
Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative (afibrinogenemia, hypofibrinogenemia) and qualitative (dysfibrinogenemia and hypodysfibrinogenemia) disorders. The clinical phenotype is highly heterogeneous,
Tomas Simurda, Rosanna Asselta, Jana Zolkova, Monika Brunclikova, Miroslava Dobrotova, Zuzana Kolkova, Dusan Loderer, Ingrid Skornova, Jan Hudecek, Zora Lasabova, Jan Stasko, Peter Kubisz   +11 more
doaj   +1 more source

Fibrinogen post-translational modifications are biochemical determinants of fibrin clot properties and interactions. [PDF]

FEBS J
The biochemical and biophysical properties of fibrinogen and fibrin, which is formed during coagulation, are critical for proper hemostatic function. The formation of abnormal fibrin clots has been linked to a prothrombotic phenotype and disease states.
Tenopoulou M.
europepmc   +2 more sources