Results 41 to 50 of about 1,246 (182)
Laboratory Diagnosis of Dysfibrinogenemia
Archives of Pathology & Laboratory Medicine, 2002 Abstract Dysfibrinogenemia is a coagulation disorder caused by a variety of structural abnormalities in the fibrinogen molecule that result in abnormal fibrinogen function. It can be inherited or acquired. The inherited form is associated with increased risk of bleeding, thrombosis, or both in the same patient or family. Traditionally,
Mark T, Cunningham +3 more
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Fibrin monomers derived from thrombogenic dysfibrinogenemia, Naples-type variant (BβAla68Thr), showed almost entirely normal polymerization [PDF]
, 2018 ArticleTHROMBOSIS RESEARCH.172:1-3(2018)journal ...
Nagata, Kazuhiro +5 more
core +1 more source
[Dysfibrinogenemia and thrombosis. A case report].
, 2010 International audienceBACKGROUND: Congenital dysfibrinogenemia is a functional disorder of the fibrinogen that represents a rare cause of thrombophilia. AIM: To report a Tunisian case of the association dysfibrinogenemia and thrombosis.
Ben Abid, Héla +3 more
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Dysfibrinogenemia and Thrombosis
Archives of Pathology & Laboratory Medicine, 2002 Abstract Objectives.—To review the state of the art relating to congenital dysfibrinogenemia as a potential risk factor for thrombosis, as reflected by the medical literature and the consensus opinion of recognized experts in the field, and to make recommendations for the use of laboratory assays for assessing this thrombotic risk in ...
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Congenital dysfibrinogenemia: fibrinogen detroit [PDF]
Journal of Clinical Investigation, 1969 A 17 yr old female with a congenital bleeding disorder was found to suffer from dysfibrinogenemia. Whole blood and plasma coagulation times were delayed and thrombelastograms were grossly abnormal. Clottability of plasma fibrinogen by addition of thrombin was not demonstrated during the 30 min test period.
E F, Mammen +3 more
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Dysfibrinogenemia Associated with Liver Disease [PDF]
Journal of Clinical Investigation, 1977 To test the possibility that a functionally abnormal fibrinogen may exist in some patients with liver disease, we studied the plasma and purified fibrinogens of five patients whose plasma thrombin times were prolonged at least 40% over normal controls. In no patient was there evidence of disseminated intravascular coagulation and/or fibrinolysis.
J E, Palascak, J, Martinez
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International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Fibrinogen deficiency is an important coagulation abnormality, with diverse causes. Methods A consecutive‐case cohort study of adult and pediatric patients with low Clauss fibrinogen at four acute care hospitals was undertaken to explore findings, causes, and predictors of outcomes, including the optimal fibrinogen critical value ...
Natalie Mathews +7 more
wiley +1 more source
Open Medicine, 2020 Congenital dysfibrinogenemia (CD) is a rare hereditary fibrinogen disorder characterized by normal fibrinogen antigen levels associated with lower functional activities.
Qiao Yingli +3 more
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Italian Journal of Medicine, 2020 Thrombophilia or hypercoagulable state is a predisposition to form clots. Thrombophilia can be inherited or acquired, and prevalently involves venous vessels.
Federico Cacciapuoti
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Diagnostics, 2021 Congenital fibrinogen disorders are rare pathologies of the hemostasis, comprising quantitative (afibrinogenemia, hypofibrinogenemia) and qualitative (dysfibrinogenemia and hypodysfibrinogenemia) disorders. The clinical phenotype is highly heterogeneous,
Tomas Simurda +11 more
doaj +1 more source