Results 61 to 70 of about 1,246 (182)

Digital ischemia and gangrene due to red blood cell aggregation induced by acquired dysfibrinogenemia [PDF]

, 1997
Digital gangrene was observed in a patient who had angiographic findings of digital arterial occlusion. The patient's blood showed a marked red blood cell aggregation with rouleaux formation in long chains, which could not be dispersed at shear rates up ...
Sakurai, Shumpei, Levin, Murray, Kauffman, John W., Rooney, Michael W., Kucuk, Omer, Kwaan, Hau C., Lis, Leonard J.   +6 more
core   +1 more source

Fibrinogen deficiency in a dog - a case report

BMC Veterinary Research, 2017
Background Among coagulation disorders, primary fibrinogen deficiency is very rare in dogs. It is divided into hypofibrinogenemia, afibrinogenemia and dysfibrinogenemia. Afibrinogenemia has been described in three dogs.
Franck Jolivet, Armelle Diquélou, Catherine Trumel, Simon Privat, Olivier Dossin   +4 more
doaj   +1 more source

The Effect of Hepatitis B Infection on Levels of Fibrinogen, Protein C, and Protein S in Pregnant Women

Journal of Pregnancy, Volume 2026, Issue 1, 2026.
Background Viral hepatitis has been associated with profound alterations in the coagulation system as well as liver biomarkers. Meanwhile, during pregnancy, the coagulation system also undergoes significant changes with an increase in the majority of the clotting factors and a decrease in natural anticoagulants.
Abiba Alhassan Khalifah, Stephen Twumasi, Allwell Adofo Ayirebi, Wina Ivy Ofori Boadu, Francis Agyei Amponsah, Joseph Frimpong, David Amoah Afrifah, Ernest Appiagyei, Albert Ntim Boadu, Daniel Nii Martey Antonio, Enoch Odame Anto, Nidhi Chaudhary   +11 more
wiley   +1 more source

Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

Bleeding, Thrombosis and Vascular Biology
Background: inherited fibrinogen disorders are characterized by a spectrum of quantitative or qualitative fibrinogen deficiency associated with both a hemorrhagic and thrombotic risk.
Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro   +9 more
doaj   +1 more source

DYSFIBRINOGENEMIA IN BURNED CHILDREN [PDF]

Pediatric Research, 1989
Severely burned children often show a dysfunction of microcirculation, due to overproduction of O2 radicals and to the activation of blood coagulation. We studied the effect of H2O2 on fibrinogen collected from burned children. Controls were healthy adult donors. Fibrinogen was purified through precipitation with PEG and saltin-out procedure.
Domenico Del Principe, Adriana Menichelli, Massimo Giordani, Carlo M Colucci, Claudio Colistra, Stefano Di Giulio   +5 more
openaire   +1 more source

Hereditary hypofibrinogenemia: A rare cause of chronic liver disease

JPGN Reports, Volume 6, Issue 4, Page 524-526, November 2025.
Abstract Hypofibrinogenemia is characterized by low levels of fibrinogen with patients commonly presenting asymptomatically. This report discusses a case of hereditary hypofibrinogenemia manifesting as chronic liver disease in a 2‐year‐old male who was evaluated for elevated liver enzymes and skin/soft tissue bleeding.
Hannah Caringal, Nolan Maloney, Khyati Mehta, Akshat Jain, Kalyan Parashette   +4 more
wiley   +1 more source

Current Practice Regarding Bleeding Disorders of Unknown Cause in the Netherlands: A National Survey

Haemophilia, Volume 31, Issue 4, Page 752-760, July 2025.
ABSTRACT Introduction About 40%–70% of persons with a clinically relevant bleeding tendency who are referred to haemostasis experts are classified as having a ‘bleeding disorder of unknown cause’ (BDUC) as no biological entity can be found after extensive laboratory testing.
Caroline M. A. Mussert, Amaury L. L. Monard, Tirsa T. van Duijl, Yvonne M. C. Henskens, Maartje van den Biggelaar, Roger E. G. Schutgens, Saskia E. M. Schols, Karin J. Fijnvandraat, Karina Meijer, Paul L. den Exter, Laurens Nieuwenhuizen, Iris van Moort, Marieke J. H. A. Kruip, Marjon H. Cnossen, Floor C. J. I. Heubel‐Moenen, for the BDUC‐iN study group   +15 more
wiley   +1 more source

Dysfibrinogenemia and hypofibrinogenemia - Spectrum of pathogenic variants in Slovak patients

Biomedical Papers
Introduction. Congenital hypofibrinogenemia (CH) and congenital dysfibrinogenemia (CD) are rare coagulation disorders caused by quantitative or qualitative defects in the fibrinogen gene.
Dominika Jaraskova, Jan Chandoga, Angelika Batorova, Tatiana Prigancova, Miriama Juhosova, Pavol Durina, Alzbeta Vavrova, Silvia Dallemule, Robert Petrovic, Anna Kyselova, Denisa Jankovicova, Daniel Bohmer   +11 more
doaj   +1 more source

Integrating Next‐Generation Sequencing Into Routine Molecular Diagnosis of Inherited Coagulation Factor Deficiencies: Real‐World Data From Spanish Patients

Haemophilia, Volume 31, Issue 4, Page 734-742, July 2025.
ABSTRACT Introduction Inherited coagulation factor deficiencies (ICFD) result from plasma protein deficiencies, impacting blood coagulation cascade and leading to haemorrhagic diathesis. Advancements in next‐generation sequencing (NGS) technology have enabled high‐throughput methods for molecular ICFD diagnosis.
Nina Borràs, Natàlia Comes, Lorena Ramírez, Rafael Parra, Carmen Altisent, Álvaro Lorenzo‐Vizcaya, Cristina Marzo‐Alonso, Maria‐Fernanda López‐Fernández, Mariana Canaro, María Falcón‐Rodríguez, Ángela Cortes‐Vidal, Mario A. Rios de Paz, José Antonio Rodríguez‐García, Ana Moreto‐Quintana, Perla Bandini, Carlos Hobeich, Irene Corrales, Francisco Vidal   +17 more
wiley   +1 more source

A novel Asp344Val substitution in the fibrinogen gamma chain (fibrinogen Caen) causes dysfibrinogenemia associated with thrombosis

, 2008
A 5-year-old boy was hospitalized for acute appendicitis. Routine preoperative hemostasis screening resulted in a diagnosis of dysfibrinogenemia. Fifteen days after the operation the patient was re-hospitalized for deep vein thrombosis.
De Moerloose, Philippe, Gandon-Laloum, Sylvie, Robert-Ebadi, Helia, Neerman Arbez, Marguerite, Borel Derlon, Annie, Le Querrec, Agnès   +5 more
core   +1 more source