Results 51 to 60 of about 1,945 (206)

Thrombophilias: therapeutic employment of direct oral anticoagulants in venous hypercoagulable states

Italian Journal of Medicine, 2020
Thrombophilia or hypercoagulable state is a predisposition to form clots. Thrombophilia can be inherited or acquired, and prevalently involves venous vessels.
Federico Cacciapuoti
doaj   +1 more source

Chronic Thromboembolic Pulmonary Hypertension: A Review of the Multifaceted Pathobiology

Biomedicines, 2023
Chronic thromboembolic pulmonary disease results from the incomplete resolution of thrombi, leading to fibrotic obstructions. These vascular obstructions and additional microvasculopathy may lead to chronic thromboembolic pulmonary hypertension (CTEPH ...
Hakim Ghani, Joanna Pepke-Zaba
doaj   +1 more source

The urgent need to develop novel strategies for the diagnosis and treatment of snakebites [PDF]

, 2019
Snakebite envenoming (SBE) is a priority neglected tropical disease, which kills over one hundred thousand people per year. However, many millions of survivors also suffer through disabilities and long-term health consequences.
Aagaard-Hansen, Abbas, Bdolah, Bicknell, , Blaylock, Bouazza, Chippaux, CSL, Dhananjaya, Fry, Griffin, Harvey, Kalita, Kardong, Kardong, Kisiel, Kisiel, Layfield, , Litschka-Koen, Mackessy, Modahl, Omidfar, Ottesen, Patel, , Paul, Schetinger, Seth, Shah, Trim, , Vaiyapuri, Vaiyapuri, , Vallance, , Vijeth, Warrell, Warrell, Warrell, Wei, Williams, , Wüster, Zolfagharian   +39 more
core   +1 more source

Development and validation of a novel qualitative test for plasma fibrinogen utilizing clot waveform analysis

Scientific Reports, 2022
Plasma fibrinogen is commonly examined by Clauss fibrinogen assay, which cannot distinguish between quantitative and qualitative fibrinogen anomalies. However, our previously reported Clauss fibrinogen assay utilizing clot waveform analysis (Clauss-CWA ...
Atsuo Suzuki, Nobuaki Suzuki, Takeshi Kanematsu, Sho Shinohara, Hiroshi Kurono, Nobuo Arai, Shuichi Okamoto, Naruko Suzuki, Shogo Tamura, Ryosuke Kikuchi, Akira Katsumi, Tetsuhito Kojima, Tadashi Matsushita   +12 more
doaj   +1 more source

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Congenital Hypofibrinogenemia in a Neonate with a Novel Mutation in the FGB Gene [PDF]

, 2021
ArticlePediatric reports.
Imashuku, Shinasku, Kadowaki, Sayaka, Katsuda, Itsuro, Nagasawa, Mayumi, Nishikado, Motokazu, Okumura, Nobuo, Shinozuka, Jun   +6 more
core   +1 more source

Dysfibrinogenemia and Thrombosis

Archives of Pathology & Laboratory Medicine, 2002
AbstractObjectives.—To review the state of the art relating to congenital dysfibrinogenemia as a potential risk factor for thrombosis, as reflected by the medical literature and the consensus opinion of recognized experts in the field, and to make recommendations for the use of laboratory assays for assessing this thrombotic risk in individual patients.
openaire   +2 more sources

The Swiss Haemophilia Registry–Report From the First 8 Years

Haemophilia, EarlyView.
ABSTRACT Introduction Patient registries capture disease related information and provide a valuable source for real‐world data on rare diseases and their management. The Swiss Haemophilia Registry (SHR) was established in 2015 on the basis of a new Swiss federal human research act.
Alessandra Bosch, Lorenzo Alberio, Pierre Fontana, Lukas Graf, Johanna A. Kremer Hovinga, Nicolas von der Weid, Mattia Rizzi, Manuela Albisetti, the Swiss Haemophilia Network   +8 more
wiley   +1 more source

An acquired inhibitor that produced a delay of fibrinopeptide B release in an asymptomatic patient

Haematologica, 2007
An asymptomatic, 29-year-old woman was referred to our hospital before surgery because in the basic study of hemostasis she showed a prolonged thrombin time (TT) and a normal reptilase time (RT). She had not received any anticoagulants so, to account for
D. Llobet, M. Borrell, L. Vila, C. Vallvé, R. Felices, J. Fontcuberta   +5 more
doaj   +1 more source

Resolving Differential Diagnostic Problems in von Willebrand Disease, in Fibrinogen Disorders, in Prekallikrein Deficiency and in Hereditary Hemorrhagic Telangiectasia by Next-Generation Sequencing

Life, 2021
Diagnosis of rare bleeding disorders is challenging and there are several differential diagnostics issues. Next-generation sequencing (NGS) is a useful tool to overcome these problems.
Réka Gindele, Adrienne Kerényi, Judit Kállai, György Pfliegler, Ágota Schlammadinger, István Szegedi, Tamás Major, Zsuzsanna Szabó, Zsuzsa Bagoly, Csongor Kiss, János Kappelmayer, Zsuzsanna Bereczky   +11 more
doaj   +1 more source