Results 51 to 60 of about 1,246 (182)

Analysis of plasmin generation and clot lysis of plasma fibrinogen purified from a heterozygous dysfibrinogenemia, B beta Gly15Cys (Hamamatsu II) [PDF]

open access: yes, 2015
This is a non-final version of an article published in final form in Blood Coagulation & Fibrinolysis. 20(8):726-732, December 2009.We found a heterozygous dysfibrinogenemia caused by the substitution of B beta Gly15Cys and designated it fibrinogen ...
Terasawa, Fumiko   +5 more
core   +2 more sources

Multigenic forms of thrombophilia in habitual miscarige. [PDF]

open access: yesMedičnì Perspektivi, 2015
Miscarriage is an actual problem of modern obstetrics. The frequency of miscarriage is 10-25% of all pregnancies, and habitual abortion occurs in 5%. Habitual miscarriage is considered as a typical multifactorial disease, being the result of expression ...
K. V. Voronin   +2 more
doaj   +2 more sources

Measurement of Active Thrombin Bound to Circulating D‐Dimers as a Sensitive Biomarker for Prothrombotic Conditions

open access: yesJournal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
Scheme of preparation of D‐dimers and evaluation of D‐dimer‐bound thrombin activity. Thrombin bound to fibrin participates in ongoing fibrinogen transformation and its inhibition is impeded. Our detection system may aid in identifying patients at risk of recurrent thrombotic events or complications, regardless of the origin of the acute health problem.
Jana Stikarova   +15 more
wiley   +1 more source

Acquired dysfibrinogenemia: monoclonal λ-type IgA binding to fibrinogen caused lower functional plasma fibrinogen level and abnormal clot formation [PDF]

open access: yes, 2020
ArticleInternational journal of hematology. 112(1): 96-104.
Takezawa, Yuka   +8 more
core   +1 more source

An acquired inhibitor that produced a delay of fibrinopeptide B release in an asymptomatic patient

open access: yesHaematologica, 2007
An asymptomatic, 29-year-old woman was referred to our hospital before surgery because in the basic study of hemostasis she showed a prolonged thrombin time (TT) and a normal reptilase time (RT). She had not received any anticoagulants so, to account for
D. Llobet   +5 more
doaj   +1 more source

Chronic Thromboembolic Pulmonary Hypertension: A Review of the Multifaceted Pathobiology

open access: yesBiomedicines, 2023
Chronic thromboembolic pulmonary disease results from the incomplete resolution of thrombi, leading to fibrotic obstructions. These vascular obstructions and additional microvasculopathy may lead to chronic thromboembolic pulmonary hypertension (CTEPH ...
Hakim Ghani, Joanna Pepke-Zaba
doaj   +1 more source

Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation

open access: yesAmerican Journal of Hematology, Volume 101, Issue 4, Page 794-806, April 2026.
ABSTRACT Postpartum hemorrhage (PPH) remains the leading cause of preventable maternal mortality despite standard interventions. Recent fibrinogen trials failed to improve outcomes, prompting interest in coagulation factor XIII (FXIII). FXIII functions as “molecular cement,” cross‐linking fibrin and stabilizing clots.
Jeremy W. Jacobs   +8 more
wiley   +1 more source

Fibrinogen dysfunction and fibrinolysis state in patients with hepatitis B-related cirrhosis

open access: yesHematology
Objective To assess the fibrinogen function in patients with hepatitis B-related cirrhosis and explore the relationship between dysfibrinogenemia and bleeding and thrombotic events.Methods Medical records and laboratory data of the patients with ...
Yu Liu   +5 more
doaj   +1 more source

Development and validation of a novel qualitative test for plasma fibrinogen utilizing clot waveform analysis

open access: yesScientific Reports, 2022
Plasma fibrinogen is commonly examined by Clauss fibrinogen assay, which cannot distinguish between quantitative and qualitative fibrinogen anomalies. However, our previously reported Clauss fibrinogen assay utilizing clot waveform analysis (Clauss-CWA ...
Atsuo Suzuki   +12 more
doaj   +1 more source

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

open access: yesAmerican Journal of Hematology, Volume 101, Issue 1, Page 97-109, January 2026.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi   +11 more
wiley   +1 more source

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