Results 31 to 40 of about 215 (110)

The roadmap for allergology in Europe: The European training requirements for the specialty of allergology

, 2021
Allergy, Volume 76, Issue 5, Page 1588-1591, May 2021.
Roy Gerth van Wijk, Norbert Mülleneisen, Pascal Demoly, Jose Maria Olaguibel, Todor A. Popov, Peter Schmid‐Grendelmeier, Olympia Tsilochristou   +6 more
wiley   +1 more source

CD8+ T‐cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations

Journal of Clinical Laboratory Analysis, Volume 34, Issue 9, September 2020., 2020
Abstract Background Dyskeratosis congenita (DC) is a syndrome resulting from defective telomere maintenance. Immunodeficiency associated with DC can cause significant morbidity and lead to premature mortality, but the immunological characteristics and molecular hallmark of DC patients, especially young patients, have not been described in detail ...
Ting Zeng, Ge Lv, Xuemei Chen, Lu Yang, Lina Zhou, Ying Dou, Xuemei Tang, Jun Yang, Yunfei An, Xiaodong Zhao   +9 more
wiley   +1 more source

Diagnostic challenges for a novel SH2D1A mutation associated with X‐linked lymphoproliferative disease

Pediatric Blood &Cancer, Volume 67, Issue 4, April 2020., 2020
Abstract Mutations in SH2D1A, encoding the intracellular adaptor signaling lymphocyte activation molecule associated protein (SAP), are associated with X‐linked lymphoproliferative disease type 1 (XLP1). We identified a novel hemizygous SH2D1A c.49G > A (p.E17K) variant in a 21‐year‐old patient with fatal Epstein‐Barr virus infection–associated ...
Lamberto Torralba‐Raga, Bianca Tesi, Samuel C. C. Chiang, Heinrich Schlums, Magnus Nordenskjöld, AnnaCarin Horne, Jan‐Inge Henter, Marie Meeths, Mohamed Abdelhaleem, Sheila Weitzman, Yenan Bryceson   +10 more
wiley   +1 more source

Aspergilloma Superimposed Infection on Lymphoid Interstitial Pneumonia

Case Reports in Emergency Medicine, Volume 2020, Issue 1, 2020., 2020
We describe a case of a 27‐year‐old female without any prior underlying immunodeficiency syndromes who presented with hemoptysis secondary to subacute invasive pulmonary aspergillosis and subsequently diagnosed with lymphoid interstitial pneumonia (LIP). CT chest demonstrated bilateral interstitial disease with patchy opacities and multiple large cysts
Daniel Tran, Rajagopalan Rengan, James Lee, Alan Lucerna, James Espinosa, Vasileios Papadopoulos   +5 more
wiley   +1 more source

CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development.

PLoS ONE, 2016
The SLAM family receptors contribute to diverse aspects of lymphocyte biology and signal via the small adaptor molecule SAP. Mutations affecting SAP lead to X-linked lymphoproliferative syndrome Type 1, a severe immunodysregulation characterized by ...
Bonnie Huang, Julio Gomez-Rodriguez, Silvia Preite, Lisa J Garrett, Ursula L Harper, Pamela L Schwartzberg   +5 more
doaj   +1 more source

Follicular Helper T Cells in DiGeorge Syndrome

Frontiers in Immunology, 2018
DiGeorge syndrome is an immunodeficiency characterized by thymic dysplasia resulting in T cell lymphopenia. Most patients suffer from increased susceptibility to infections and heightened prevalence of autoimmune disorders, such as autoimmune ...
Adam Klocperk, Adam Klocperk, Zuzana Paračková, Markéta Bloomfield, Michal Rataj, Jan Pokorný, Susanne Unger, Klaus Warnatz, Anna Šedivá   +8 more
doaj   +1 more source

The association between Kaposi's sarcoma and dysgammaglobulinemia [PDF]

Cancer, 1982
The case of a patient with Kaposi's sarcoma and paraproteinemia is described and the relevant literature is reviewed. It is suggested that Kaposi's sarcoma is part of the spectrum of the lymphoproliferative diseases, and that both the marked angiogenesis and the synthesis of paraproteins in this disease are different expressions of the same ...
E, Ben-Chetrit, D, Ben-Amitai, Y, Levo
openaire   +2 more sources

EBV Infection in XLP1 Manifested Solely by Behavioral Aggression and Effective Treatment Using Rituximab

Case Reports in Immunology, Volume 2018, Issue 1, 2018., 2018
Patients with X‐linked lymphoproliferative disease 1 (XLP1) are exquisitely susceptible to Epstein‐Barr virus (EBV), with the first EBV infection often resulting in rapid death. In a manner not previously described, a 5‐year‐old patient with XLP1 presented solely with behavioral aggression, with no laboratory evidence of organ dysfunction or ...
Michelle M. Korah-Sedgwick, Luke A. Wall, Alessandro Plebani   +2 more
wiley   +1 more source

Synchronous BALT Lymphoma and Squamous Cell Carcinoma of the Lung: Coincidence or Linkage?

Case Reports in Oncological Medicine, Volume 2013, Issue 1, 2013., 2013
A 72‐year‐old man presented with weight loss, fever, and malaise. Chest radiograph and CT revealed two large ill‐defined masses in middle and left lower lobes. CT‐guided biopsy of left lower lobe mass disclosed bronchus‐associated lymphoid tissue (BALT) lymphoma. Middle lobe mass was considered second deposit in contralateral lung. The patient received
Anastasia Oikonomou, Emanuelle Astrinakis, Ioannis Kotsianidis, Vassiliki Kaloutsi, Vassileios Didilis, Konstantinos Tsatalas, Panos Prassopoulos, B. I. Razzouk, M. Ryberg, K. Tanaka, D. Yin, N. Yoshimura   +11 more
wiley   +1 more source

Multifaceted roles of IKZF1 gene, perspectives from bench to bedside

Frontiers in Oncology
The IKZF1 gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The protein product, IKAROS, had been proved to regulate lymphopoiesis. Subsequent mouse model studies have
Lin Feng, Hang Zhang, Ting Liu
doaj   +1 more source