Results 31 to 40 of about 1,006 (159)

CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development.

open access: yesPLoS ONE, 2016
The SLAM family receptors contribute to diverse aspects of lymphocyte biology and signal via the small adaptor molecule SAP. Mutations affecting SAP lead to X-linked lymphoproliferative syndrome Type 1, a severe immunodysregulation characterized by ...
Bonnie Huang   +5 more
doaj   +1 more source

Children with Tourette’s Syndrome May Suffer Immunoglobulin A Dysgammaglobulinemia: Preliminary Report

open access: yesBiological Psychiatry, 2009
Background Postinfectious autoimmunity has been implicated in Tourette’s syndrome and obsessive-compulsive disorder (TS/OCD), whereas increased frequency of upper respiratory tract infections (URTI) in TS/OCD patients suggests immune deficiency.
I. Kawikova   +9 more
semanticscholar   +1 more source

Follicular Helper T Cells in DiGeorge Syndrome

open access: yesFrontiers in Immunology, 2018
DiGeorge syndrome is an immunodeficiency characterized by thymic dysplasia resulting in T cell lymphopenia. Most patients suffer from increased susceptibility to infections and heightened prevalence of autoimmune disorders, such as autoimmune ...
Adam Klocperk   +8 more
doaj   +1 more source

EBV Infection in XLP1 Manifested Solely by Behavioral Aggression and Effective Treatment Using Rituximab

open access: yesCase Reports in Immunology, Volume 2018, Issue 1, 2018., 2018
Patients with X‐linked lymphoproliferative disease 1 (XLP1) are exquisitely susceptible to Epstein‐Barr virus (EBV), with the first EBV infection often resulting in rapid death. In a manner not previously described, a 5‐year‐old patient with XLP1 presented solely with behavioral aggression, with no laboratory evidence of organ dysfunction or ...
Michelle M. Korah-Sedgwick   +2 more
wiley   +1 more source

Synchronous BALT Lymphoma and Squamous Cell Carcinoma of the Lung: Coincidence or Linkage?

open access: yesCase Reports in Oncological Medicine, Volume 2013, Issue 1, 2013., 2013
A 72‐year‐old man presented with weight loss, fever, and malaise. Chest radiograph and CT revealed two large ill‐defined masses in middle and left lower lobes. CT‐guided biopsy of left lower lobe mass disclosed bronchus‐associated lymphoid tissue (BALT) lymphoma. Middle lobe mass was considered second deposit in contralateral lung. The patient received
Anastasia Oikonomou   +11 more
wiley   +1 more source

An Overlapping Syndrome of Allergy and Immune Deficiency in Children

open access: yesJournal of Allergy, Volume 2012, Issue 1, 2012., 2012
Recurrent airway inflammations in children are an important clinical problem in pediatric practice. An essential challenge is differentiation between allergic background and immune deficiency, which is a difficult task taking into consideration individual predisposition to atopy, immune system maturation in the early childhood, as well as exposition to
Aleksandra Szczawinska-Poplonyk   +1 more
wiley   +1 more source

Hematopoiesis and immune reconstitution after CD19 directed chimeric antigen receptor T‐cells (CAR‐T): A comprehensive review on incidence, risk factors and current management

open access: yesEuropean Journal of Haematology, Volume 112, Issue 2, Page 184-196, February 2024.
Abstract Impaired function of hematopoiesis after treatment with chimeric antigen T‐cells (CAR‐T) is a frequent finding and can interest a wide range of patients, regardless of age and underlying disease. Trilinear cytopenias, as well as hypogammaglobulinemia, B‐cell aplasia, and T‐cell impairment, can severely affect the infectious risk of CAR‐T ...
Eugenio Galli   +13 more
wiley   +1 more source

Pediatric Selective IgM Immunodeficiency

open access: yesJournal of Immunology Research, Volume 2008, Issue 1, 2008., 2008
Objective. Limited information exists on features of pediatric Selective IgM immunodeficiency (SIgMID). Previously published pediatric cases and 2 new cases are reviewed. Methods. English literature from PubMed and references from relevant articles were reviewed.
Marc F. Goldstein   +6 more
wiley   +1 more source

"Primary Immunodeficiencies Inducing EBV-Associated Severe Illnesses "

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2004
Epstein-Barr virus (EBV) is a ubiquitous human -herpesvirus that infects about 95% of the adult population. The majority of primary infections occurs in early childhood and is generally subclinical; it can cause infectious mononucleosis (IM), which is ...
Toshio Miyawaki
doaj  

A PATIENT WITH NEMO SYNDROME AND DYSGAMMAGLOBULINEMIA DEVELOPS IGA NEPHROPATHY REQUIRING RENAL TRANSPLANT.

open access: yesAnnals of Allergy, Asthma & Immunology, 2023
N. Makkoukdji   +4 more
semanticscholar   +1 more source

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