Results 31 to 40 of about 1,006 (159)
The SLAM family receptors contribute to diverse aspects of lymphocyte biology and signal via the small adaptor molecule SAP. Mutations affecting SAP lead to X-linked lymphoproliferative syndrome Type 1, a severe immunodysregulation characterized by ...
Bonnie Huang +5 more
doaj +1 more source
Background Postinfectious autoimmunity has been implicated in Tourette’s syndrome and obsessive-compulsive disorder (TS/OCD), whereas increased frequency of upper respiratory tract infections (URTI) in TS/OCD patients suggests immune deficiency.
I. Kawikova +9 more
semanticscholar +1 more source
Follicular Helper T Cells in DiGeorge Syndrome
DiGeorge syndrome is an immunodeficiency characterized by thymic dysplasia resulting in T cell lymphopenia. Most patients suffer from increased susceptibility to infections and heightened prevalence of autoimmune disorders, such as autoimmune ...
Adam Klocperk +8 more
doaj +1 more source
Patients with X‐linked lymphoproliferative disease 1 (XLP1) are exquisitely susceptible to Epstein‐Barr virus (EBV), with the first EBV infection often resulting in rapid death. In a manner not previously described, a 5‐year‐old patient with XLP1 presented solely with behavioral aggression, with no laboratory evidence of organ dysfunction or ...
Michelle M. Korah-Sedgwick +2 more
wiley +1 more source
Synchronous BALT Lymphoma and Squamous Cell Carcinoma of the Lung: Coincidence or Linkage?
A 72‐year‐old man presented with weight loss, fever, and malaise. Chest radiograph and CT revealed two large ill‐defined masses in middle and left lower lobes. CT‐guided biopsy of left lower lobe mass disclosed bronchus‐associated lymphoid tissue (BALT) lymphoma. Middle lobe mass was considered second deposit in contralateral lung. The patient received
Anastasia Oikonomou +11 more
wiley +1 more source
An Overlapping Syndrome of Allergy and Immune Deficiency in Children
Recurrent airway inflammations in children are an important clinical problem in pediatric practice. An essential challenge is differentiation between allergic background and immune deficiency, which is a difficult task taking into consideration individual predisposition to atopy, immune system maturation in the early childhood, as well as exposition to
Aleksandra Szczawinska-Poplonyk +1 more
wiley +1 more source
Abstract Impaired function of hematopoiesis after treatment with chimeric antigen T‐cells (CAR‐T) is a frequent finding and can interest a wide range of patients, regardless of age and underlying disease. Trilinear cytopenias, as well as hypogammaglobulinemia, B‐cell aplasia, and T‐cell impairment, can severely affect the infectious risk of CAR‐T ...
Eugenio Galli +13 more
wiley +1 more source
Pediatric Selective IgM Immunodeficiency
Objective. Limited information exists on features of pediatric Selective IgM immunodeficiency (SIgMID). Previously published pediatric cases and 2 new cases are reviewed. Methods. English literature from PubMed and references from relevant articles were reviewed.
Marc F. Goldstein +6 more
wiley +1 more source
"Primary Immunodeficiencies Inducing EBV-Associated Severe Illnesses "
Epstein-Barr virus (EBV) is a ubiquitous human -herpesvirus that infects about 95% of the adult population. The majority of primary infections occurs in early childhood and is generally subclinical; it can cause infectious mononucleosis (IM), which is ...
Toshio Miyawaki
doaj

