Results 41 to 50 of about 215 (110)

Changes in Serum Immunoglobulin Levels Play as Predictors of Treatment Response and Prognosis in Pediatric Idiopathic Nephrotic Syndrome During the Remission Phase

Immunity, Inflammation and Disease, Volume 13, Issue 1, January 2025.
ABSTRACT Background Nephrotic syndrome is an immune‐mediated renal disorder characterized by T‐cell and B‐cell dysfunctions with changes in immunoglobulin (Ig) levels and the IgG:IgM ratio. Therefore, this study aimed to determine whether the serum level of Igs can be considered as an index to predict the response to treatment and the prognosis of ...
Amin sadat Sharif, Naghmeh Nickravesh, Marzieh Heidarzadeh Arani, Mohammad Javad Azadchehr, Hossein Motedayyen   +4 more
wiley   +1 more source

An Overlapping Syndrome of Allergy and Immune Deficiency in Children

Journal of Allergy, Volume 2012, Issue 1, 2012., 2012
Recurrent airway inflammations in children are an important clinical problem in pediatric practice. An essential challenge is differentiation between allergic background and immune deficiency, which is a difficult task taking into consideration individual predisposition to atopy, immune system maturation in the early childhood, as well as exposition to
Aleksandra Szczawinska-Poplonyk, Mary Beth Hogan   +1 more
wiley   +1 more source

Hematopoiesis and immune reconstitution after CD19 directed chimeric antigen receptor T‐cells (CAR‐T): A comprehensive review on incidence, risk factors and current management

European Journal of Haematology, Volume 112, Issue 2, Page 184-196, February 2024.
Abstract Impaired function of hematopoiesis after treatment with chimeric antigen T‐cells (CAR‐T) is a frequent finding and can interest a wide range of patients, regardless of age and underlying disease. Trilinear cytopenias, as well as hypogammaglobulinemia, B‐cell aplasia, and T‐cell impairment, can severely affect the infectious risk of CAR‐T ...
Eugenio Galli, Alberto Fresa, Silvia Bellesi, Elisabetta Metafuni, Elena Maiolo, Ilaria Pansini, Filippo Frioni, Francesco Autore, Maria Assunta Limongiello, Idanna Innocenti, Sabrina Giammarco, Patrizia Chiusolo, Gina Zini, Federica Sorà   +13 more
wiley   +1 more source

Pediatric Selective IgM Immunodeficiency

Journal of Immunology Research, Volume 2008, Issue 1, 2008., 2008
Objective. Limited information exists on features of pediatric Selective IgM immunodeficiency (SIgMID). Previously published pediatric cases and 2 new cases are reviewed. Methods. English literature from PubMed and references from relevant articles were reviewed.
Marc F. Goldstein, Alex L. Goldstein, Eliot H. Dunsky, Donald J. Dvorin, George A. Belecanech, Kfir Shamir, Chikao Morimoto   +6 more
wiley   +1 more source

Linkage of autosomal-dominant common variable immunodeficiency to chromosome 4q. [PDF]

, 2006
Contains fulltext : 50715.pdf (Publisher’s version ) (Closed access)The phenotype of common variable immunodeficiency (CVID) is characterized by recurrent infections owing to hypogammaglobulinemia, with deficiency in immunoglobulin (Ig ...
Finck, A, Grimbacher, B, Webster, A. David B., Schäffer, Alejandro A., Pfannstiel, J., Anemone Finck, A David B Webster, Lennart Hammarström, Pfannstiel, Jessica, Pfannstiel, J, Webster, A.D., Grimbacher, B., Claire Fieschi, Alessandro Plebani, Finck, Anemone, Fieschi, C., Jessica Pfannstiel, Schaffer, AA, Webster, ADB, Alejandro A Schäffer, Schaffer, A.A., Hammarstrom, L., Meer, Jos W. M. van der, Meer, J.W.M. van der, Bodo Grimbacher, Plebani, A., Jos W M Van der Meer, Plebani, Alessandro, Grimbacher, Bodo, Finck, A., Hammarstrom, L, Van, der Meer JWM, Fieschi, Claire, Hammarström, Lennart, Plebani, A, Fieschi, C   +35 more
core   +1 more source

"Primary Immunodeficiencies Inducing EBV-Associated Severe Illnesses "

Iranian Journal of Allergy, Asthma and Immunology, 2004
Epstein-Barr virus (EBV) is a ubiquitous human -herpesvirus that infects about 95% of the adult population. The majority of primary infections occurs in early childhood and is generally subclinical; it can cause infectious mononucleosis (IM), which is ...
Toshio Miyawaki
doaj  

Immunoelectrophoresis Versus Electrophoresis in Study of Dysgammaglobolinemia [PDF]

, 1968
1968-09The total 476 sera were examined by a routine electrophoresis and further by the use of immunoelectrophoresis. 1) Among the 42 broad banded hypergammaglobulinemics, neither M-components nor a lack of any class of immunoglobulin was detected.
ISOBE, TAKASHI
core   +1 more source

A Novel De Novo NFKBIA missense mutation associated to ectodermal dysplasia with dysgammaglobulinemia

, 2022
Inborn errors of immunity (IEIs) are comprised of heterogeneous groups of genetic disorders affecting immune function. In this report, a 17-month-old Malay patient suspected of having Hyper IgM syndrome, a type of IEIs, was described.
Baharin, Mohd Farid, Ripen, Adiratna Mat, Ramalingam, Kavetha, Chiow, Mei Yee, Sham, Marina, El Farran, Bader Abdul Kader, Noh, Lokman Mohd, Ismail, Intan Hakimah, Chear, Chai Teng, Mohamad, Saharuddin   +9 more
core   +2 more sources

A Critical Role for IL-21 in Regulating Immunoglobulin Production

, 2002
The cytokine interleukin-21 (IL-21) is closely related to IL-2 and IL-15, and their receptors all share the common cytokine receptor γ chain, γc, which is mutated in humans with X-linked severe combined immunodeficiency disease (XSCID).
Ozaki, K.
core   +1 more source

SLAM Family Receptors and SAP Adaptors in Immunity

, 2011
The signaling lymphocyte activation molecule (SLAM)-associated protein, SAP, was first identified as the protein affected in most cases of X-linked lymphoproliferative (XLP) syndrome, a rare genetic disorder characterized by abnormal responses to ...
Jennifer L. Cannons, Stuart G. Tangye, Pamela L. Schwartzberg   +2 more
core   +1 more source