Results 11 to 20 of about 16,889 (275)

Crocin prevents haloperidol-induced orofacial dyskinesia: possible an antioxidant mechanism [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2016
Objective(s):Long-term treatment with antipsychotics causes serious side effects such as tardive dyskinesia that characterized by abnormal movements in the orofacial region. Oxidative stress in the brain specific area is implicated in the pathophysiology
Marzyeh Kamyar   +5 more
doaj   +2 more sources

Tardive dyskinesia on clozapine: A case report

open access: yesSouth African Journal of Psychiatry, 2009
Antipsychotic-induced tardive dyskinesia is a potentially irremediable and debilitating condition with the onset most commonly associated with the use of first-generation antipsychotics.
Laila Asmal
doaj   +3 more sources

New insights into the mechanism of drug-induced dyskinesia

open access: yesCNS Spectrums, 2012
Dyskinesia is an extrapyramidal movement disorder characterized by involuntary, repetitive, irregular motions that affect the mouth and face and/or the limbs and trunk. Tardive dyskinesia (TD) is a well-known complication of long-term treatment with antipsychotic drugs.
Loonen, Anton J. M.   +1 more
openaire   +3 more sources

Pathophysiological mechanisms underlying antipsychotic-induced tardive dyskinesia

open access: yesБюллетень сибирской медицины, 2020
Purpose. To analyze the results of classical and modern studies reflecting the pathophysiological mechanisms of antipsychotic-induced tardive dyskinesia.Materials and methods. We searched for full-text publications in Russian and English in the databases
E. E. Vayman   +3 more
doaj   +3 more sources

Amantadine extended-release capsules for levodopa-induced dyskinesia in patients with Parkinson's disease

open access: yesTherapeutics and Clinical Risk Management, 2018
Vibhash D Sharma, Kelly E Lyons, Rajesh Pahwa Department of Neurology, University of Kansas Medical Center, Kansas City, KS, USA Abstract: Levodopa-induced dyskinesia (LID) is a common motor complication in patients with Parkinson’s disease on ...
Sharma VD, Lyons KE, Pahwa R
doaj   +1 more source

Co‐Expression of Tardive Dyskinesia and Drug‐Induced Parkinsonism in Rats Chronically Treated With Haloperidol [PDF]

open access: yesNeuropsychopharmacology Reports
Aim We aimed to create a rat model of drug‐induced parkinsonism and tardive dyskinesia by chronic administration of haloperidol and examine the expression of direct and indirect pathway markers in the striatum of the model rats.
Iku Kinoshita   +7 more
doaj   +2 more sources

A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

open access: yesNeurobiology of Disease, 2010
L-DOPA remains the gold-standard treatment for Parkinson's disease but causes motor fluctuations and dyskinesia. Metabotropic glutamate receptor type 5 (mGluR5) has been proposed as a target for antidyskinetic therapies.
Daniella Rylander   +9 more
doaj   +2 more sources

Berberis vulgaris alleviates Levodopa-induced dyskinesia in male mice

open access: yesHerba Polonica, 2018
Introduction: Parkinson’s disease is a chronic debilitating disease and many patients use Levodopa as a major treatment. However, this drug in long-term use causes a serious condition that is known as Levodopa-induced dyskinesia (LID). Berberis vulgaris (
Mokarian Faezeh   +2 more
doaj   +2 more sources

Failure of pyridoxine to reduce drug-induced dyskinesias [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1970
The use of pyridoxine seems to be ineffective in reducing tardive dyskinesia.
G E, Crane, I S, Turek, A A, Kurland
openaire   +2 more sources

Anticholinergic Agents Can Induce Oromandibular Dyskinesia [PDF]

open access: yesJournal of Movement Disorders, 2009
Background and Purpose: Oromandibular dyskinesia (OMD) can occur spontaneously or they can be induced by the conventional dopamine receptor antagonists.
Hee-Young Shin   +2 more
doaj   +1 more source

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