Results 21 to 30 of about 4,911,045 (202)

Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm. [PDF]

, 2013
Primary ciliary dyskinesia (PCD) is a rare, genetically heterogeneous ciliopathy disorder affecting cilia and sperm motility. A range of ultrastructural defects of the axoneme underlie the disease, which is characterised by chronic respiratory symptoms ...
Danke-Roelse, JE, Hart, S.L., Munye, Mustafa M., Scambler, PJ, Rosser, E.M., Hart, Stephen L, Beales, Philip L, Bacchelli, C, Moore, Anthony T., Chung, Eddie MK, Sloper, John J, Danke-Roelse, Jeannette E, Moore, A.T., Pals, Gerard, Beales, Philip L., Sloper, John J., Moore, Anthony T, Hogg, C, Hogg, C., Bacchelli, Chiara, Mitchison, Hannah M, Shoemark, A., Moore, AT, James, C.T., Scambler, Peter J, Chung, E.M.K., Rosser, Elisabeth M., Bacchelli, C., Shoemark, Amelia; id_orcid, Patel, M., Hogg, Claire, Onoufriadis, Alexandros, Schmidts, Miriam, Emes, R.D., Munye, Mustafa M, Hull, S., Sloper, JJ, Hull, Sarah, Beales, PL, Beales, P.L., Hart, Stephen L., Munye, MM, Schmidts, M, James, Chela T, Scambler, P.J., James, Chela T., Mitchison, H.M., nke-Roelse, J.E., Hull, S, Onoufriadis, A., Rosser, Elisabeth M, Emes, Richard D., Patel, Mitali, Pals, G., Mitchison, Hannah M., Patel, M, Pals, G, Emes, RD, Munye, M.M., James, CT, Schmidts, M., Danke-Roelse, Jeannette E., Chung, Eddie M.K., Shoemark, Amelia, Mitchison, HM, Emes, Richard D, Chung, EM, Shoemark, A, Onoufriadis, A, Sloper, J.J., Hart, SL, Rosser, EM, Scambler, Peter J.   +72 more
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Relevance of animal models to human tardive dyskinesia

Behavioral and Brain Functions, 2012
Tardive dyskinesia remains an elusive and significant clinical entity that can possibly be understood via experimentation with animal models. We conducted a literature review on tardive dyskinesia modeling.
Blanchet Pierre J, Parent Marie-Thérèse, Rompré Pierre H, Lévesque Daniel   +3 more
doaj   +1 more source

Pathophysiological mechanisms underlying antipsychotic-induced tardive dyskinesia

Бюллетень сибирской медицины, 2020
Purpose. To analyze the results of classical and modern studies reflecting the pathophysiological mechanisms of antipsychotic-induced tardive dyskinesia.Materials and methods. We searched for full-text publications in Russian and English in the databases
E. E. Vayman, N. A. Shnayder, N. G. Neznanov, R. F. Nasyrova   +3 more
doaj   +1 more source

No association of a set of candidate genes on haloperidol side effects [PDF]

, 2012
We previously investigated a sample of patients during an active phase of psychosis in the search for genetic predictors of haloperidol induced side effects.
Alessandro Serretti, Ro Serretti, Hans-Jürgen Möller (127187), Annette M. Hartmann (127183), Hans H. Stassen (127195), Drago, Antonio, Möller, Hans-Jürgen, Alessandro Serretti (127197), Hartmann, Annette M, Ina Giegling (127175), Giegling, Ina, De Ronchi, Diana, Dan Rujescu, Stassen, Hans H, Ina Giegling, Martin Schäfer, Martin Schäfer (127178), Hans H Stassen, Hartmann, Annette M., Annette M Hartmann, Annette M. Hartmann, Dan Rujescu (109427), Stassen, Hans H., Schäfer, Martin, Diana De Ronchi (127190), Antonio Drago (127172), Serretti, Alessandro, Diana De Ronchi, Hans-Jürgen Möller, Hans H. Stassen, Rujescu, Dan, Antonio Drago   +31 more
core   +2 more sources

L-dopa: main drug induced dyskinesia

São Paulo Medical Journal, 2021
Introduction: 3,4-dihydroxy-L-phenylalanine (L-dopa) is the gold standard drug for the treatment of Parkinson’s disease (PD). This disease causes degeneration of dopaminergic cells, L-dopa supplies the lack of dopamine, being effective in its treatment.
Pedro Felisberto Nogueira Viana Farah, Felipe dos Santos Souza, Felipe Oliveira Costa, Mariana Bastos Rodrigues dos Santos, Yasmim Evelyn Lisboa Barbosa   +4 more
openaire   +1 more source

Investigation of PRKN Mutations in Levodopa-Induced Dyskinesia in Parkinson’s Disease Treatment

Biomedicines, 2023
Mitophagy is an important process that participates in mitochondrial quality control. Dysfunctions in this process can be caused by mutations in genes like PRKN and are associated with the development and progression of Parkinson’s Disease (PD). The most
Ana Gabrielle Bispo, Caio S. Silva, Camille Sena-dos-Santos, Dafne Dalledone Moura, Brenda Hanae Bentes Koshimoto, Bruno Lopes Santos-Lobato, Ândrea Ribeiro-dos-Santos, Giovanna C. Cavalcante   +7 more
doaj   +1 more source

Living with primary ciliary dyskinesia: a prospective qualitative study of knowledge sharing, symptom concealment, embarrassment, mistrust, and stigma [PDF]

, 2006
Primary ciliary dyskinesia (PCD) is a chronic respiratory disease for which there is little psycho-social research and no qualitative studies of individuals living with the condition.
Whalley Simon, McManus, IC, IC McManus, McManus IC, Simon Whalley, Whalley, S   +5 more
core   +2 more sources

Antipsychotic Drug Induced Tardive Dyskinesia

International Journal of Research in Pharmaceutical Sciences, 2020
A typical antipsychotics are at a lower risk of developing extra-pyramidal symptoms (EPS). But now, atypical antipsychotics are increasingly being associated with neurological side effects such as tardive dyskinesia, tardive dystonia, akinesia, parkinsonism, akathisia, bradykinesia, tremor etc.
null Gopika S Kumar, null Divya V Nair, null Remya Raghu, null Arun K   +3 more
openaire   +1 more source

Preclinical models of levodopa-induced dyskinesia

, 2014
L -DOPA-induced dyskinesia (LID) represents one of the major limitations in the current pharmacotherapy of Parkinson's disease (PD) and affects the majority of PD patients.
Francardo, Veronica,, Cenci, M. Angela,, Lund University.   +2 more
core   +1 more source

Risperidone induced tardive dyskinesia [PDF]

, 2021
Risperidone is an atypical antipsychotic drug which has been less likely to produce extrapyramidal symptoms. The aim of this case report is to illustrate that low dose risperidone may cause tardive dyskinesia.
Harichandran, Dhanya Thirookaran, Balakrishnan, Sujatha Mangattuvalappil, Kolanchinathan, Elakkya   +2 more
core   +1 more source