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Drug-Induced Dyskinesia, Part 2: Treatment of Tardive Dyskinesia

Drugs, 2016
Dyskinesias encompass a variety of different hyperkinetic phenomenologies, particularly chorea, dystonia, stereotypies, and akathisia. The main types of drug-induced dyskinesias include levodopa-induced dyskinesia (LID) in patients with Parkinson's disease and tardive syndrome (TS), typically present in patients with psychiatric or gastrointenstinal ...
Dhanya, Vijayakumar, Joseph, Jankovic
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Drug-induced dyskinesias

Current Opinion in Neurology, 2009
Recent studies have improved our knowledge of the factors responsible for the development of dyskinesias in Parkinson's disease and the associated pathophysiology. Deep brain stimulation has been shown to be effective to treat severe tardive dyskinesias.
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Pathophysiology of drug-induced dyskinesias

Neuropharmacology, 1972
Abstract The dyskinesias produced by DOPA and prolonged treatment with phenothiazines are so similar that it is tempting to propose a common mechanism for both. The following assumptions are made: (1) Dyskinesias result from excessive inhibition of caudate neurones by dopamine. 1.
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Drug-Induced Dyskinesia, Part 1: Treatment of Levodopa-Induced Dyskinesia

Drugs, 2016
Dyskinesias encompass a variety of different hyperkinetic phenomenologies, particularly chorea, dystonia, stereotypies, and akathisia. Levodopa-induced dyskinesia (LID) is one of the main types of drug-induced dyskinesia, occurring in patients with Parkinson's disease (PD) who have been treated with levodopa for long time, but this side effect may be ...
Dhanya, Vijayakumar, Joseph, Jankovic
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Drug Induced Dyskinesia: A Critical Review

International Pharmacopsychiatry, 2017
Tardive dyskinesia (TD) has been reported to occur after the long term administration of neuroleptics. Its prevalence has been reported to vary from 0.5-56%. However, no clear relationship is established between a particular neuroleptic, its dosage and duration of administration and the diagnosis and occurrence of TD.
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Drug-Induced Tardive Dyskinesia

1981
Drug-induced tardive dyskinesia, which occurs in the course of long-term administration of psychotropic drugs, especially neuroleptics, and persists for years even after drug removal, began to be reported in the late 1950s. Since then, more than 100 investigations on this subjects have been described.
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Pathophysiological basis of drug-induced dyskinesias in Parkinson's disease

Brain Research Reviews, 2005
Drug-induced dyskinesias (DID) represent a troublesome, dose-limiting, and common complication of long-term pharmacotherapy in Parkinson's disease (PD) patients. The pathophysiological basis and clinical nature of DID is of major interest for clinicians and neuroscientists.
Milind, Deogaonkar   +1 more
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