Results 61 to 70 of about 144,659 (249)
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna+4 more
wiley +1 more source
Use of Best Practice Alerts to Improve Adherence to Evidence-Based Screening in Pediatric Diabetes Care [PDF]
Background: Youth with type 1 diabetes (T1D) are at increased risk for comorbid autoimmune conditions and long-term complications. To help with early identification of these complications, the American Diabetes Association (ADA) has published evidence ...
Bartz, Sara K+3 more
core +1 more source
Relationship between Estimated Glomerular Filtration Rate (eGFR) and Metabolic Syndrome in Japanese [PDF]
We investigated the link between renal function as evaluated by estimated glomerular filtration rate (eGFR) and metabolic syndrome in Japanese.
Makino, Hirofumi+3 more
core +1 more source
Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers
ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan+7 more
wiley +1 more source
Perbedaan Asupan Lemak, Lingkar Pinggang dan Persentase Lemak Tubuh pada Wanita Dislipidemia dan Non Dislipidemia [PDF]
Differences of fat intake, waist circumference and percentage of bodt fat in dyslipidemia and non dyslipidemia adult women: Heart disease is the leading cause of death in several countries in the world . One of the major risk factors for heart disease is
Ben D. Gamari (1932061)+6 more
core +3 more sources
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun+8 more
wiley +1 more source
Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndrome [PDF]
Diabetes and metabolic syndrome are associated with abnormal postprandial lipoprotein metabolism, with a significant delay in the clearance of many lipid parameters, including triglycerides and chylomicrons.
ARCA, Marcello
core +1 more source
In this study, the improvement effect of AMP on obesity can be attributed to the conversion of extracellular AMP to ADO through ADORA2A activation by CD73, which can promote lipolysis by reducing DNA methylation level and enhancing HSL gene transcription. These findings show the great potential of AMP in improving obesity.
Zhijuan Cui+12 more
wiley +1 more source
Vascular neurocognitive disorders and the vascular risk factors [PDF]
Dementias are clinical neurodegenerative diseases characterized by permanent and progressive transformation of cognitive functions such as memory, learning capacity, attention, thinking, language, passing judgments, calculation or orientation.
Albu, Carmen V.+7 more
core +4 more sources
In hyperlipidemic states, Long‐chain fatty acyl‐CoA synthetase 1 (ACSL1) is consistently induced, which then reprogrammes the lipid metabolism in monocytes. The accumulation of monocyte‐secreted lysophosphatidylcholine (LPC)/lysophosphatidic acid (LPA) enhances the thrombotic and inflammatory processes Then LPC/LPA axis promots activation and NETosis ...
Shuai Jiang+12 more
wiley +1 more source