Results 61 to 70 of about 12,584 (301)

Cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians: A cross sectional study [PDF]

open access: yes, 2014
ObjectiveTo determine levels of cholesterol lipoproteins and prevalence of dyslipidemias in urban Asian Indians.MethodsPopulation based 6123 subjects (men 3388) were evaluated.
Arvind Gupta   +21 more
core   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

open access: yesAdvanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An   +11 more
wiley   +1 more source

Odds ratio of dyslipidemias and elevated AIP by serum 25(OH)D levels in men and women.

open access: yes, 2016
Odds ratio of dyslipidemias and elevated AIP by serum 25(OH)D levels in men and women.
Kai Feng (502124)   +7 more
core   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

open access: yesAdvanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li   +8 more
wiley   +1 more source

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

open access: yesAdvanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian   +9 more
wiley   +1 more source

Paradoxical effect of lipid lowering therapy in homozygous familial hypercholesterolemia: Atherosclerotic plaque calcifications and increased cardiovascular events

open access: yesRevista Portuguesa de Cardiologia, 2022
Tiziana Sampietro   +3 more
doaj   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

open access: yesAdvanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo   +14 more
wiley   +1 more source

Lipoprotein(a) in familial hypercholesterolemia: Tips from family history

open access: yesRevista Portuguesa de Cardiologia, 2021
Beatrice Dal Pino   +4 more
doaj   +1 more source

Update on the clinical utility of fenofibrate in mixed dyslipidemias: mechanisms of action and rational prescribing

open access: yes, 2008
Michel FarnierPoint Médical, Dijon, FranceAbstract: Mixed dyslipidemia is a common lipid disorder characterized by the presence of an atherogenic lipoprotein phenotype due to abnormalities in various atherogenic and antiatherogenic lipoproteins ...
Michel Farnier
core  

Lipoprotein(a) and family history of cardiovascular disease in children with familial dyslipidemias.

open access: yes, 2011
OBJECTIVE: To investigate in children and adolescents with familial dyslipidemias the association between lipoprotein(a) [Lp(a)] level and family history of cardiovascular disease (CVD), and whether this association is independent of the disturbed ...
Guardamagna O   +3 more
core   +1 more source

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