Results 81 to 90 of about 17,140 (296)

Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques [PDF]

, 2016
Additional file 1. General method for isolation of stromal-vascular-fraction (AT-SVF) cells from adipose tissue of rhesus macaques, and subsequent analyses.
Ashok Balasubramanyam, Dorothy E. Lewis, Jacob Couturier, K. Jagannadha Sastry, Michael A. Barry, Neeti Agarwal, Pramod N. Nehete, Wallace B. Baze   +7 more
core   +7 more sources

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

Differential lipid metabolism in monocytes and macrophages: influence of cholesterol loading[S]

Journal of Lipid Research, 2016
The influence of the hypercholesterolemia associated with atherosclerosis on monocytes is poorly understood. Monocytes are exposed to high concentrations of lipids, particularly cholesterol and lysophosphatidylcholine (lyso-PC).
Irene Fernandez-Ruiz, Patrycja Puchalska, Chandrakala Aluganti Narasimhulu, Bhaswati Sengupta, Sampath Parthasarathy   +4 more
doaj   +1 more source

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source

A PCSK9 e sua relevância clínica com os novos alvos terapêuticos contra a dislipidemia [PDF]

, 2012
This is a remarkable progress; since the finding of statins, there was no new way of reducing, significantly, cholesterol and LDL fraction. It is also clear that this decrease, by statins, is related to future cardiovascular lesions, being useful in its ...
Ferreira, Carlos Eduardo dos Santos, Fonseca, Francisco Antonio Helfenstein, Mangueira, Cristóvão Luis Pitangueiras   +2 more
core   +1 more source

An ultra‐processed food‐based cafeteria diet induces obesity, metabolic dysfunction, and tissue‐specific gene dysregulation in C57BL/6 mice

Animal Models and Experimental Medicine, EarlyView.
This schematic figure illustrates the experimental design and key findings of the study. Forty male C57BL/6 mice were assigned to either a standard diet control group or a cafeteria diet (CAFD) group for 16 weeks. CAFD induces obesity, insulin resistance (HOMA‐IR), hepatic steatosis, and dysregulation of a number of genes in visceral and subcutaneous ...
Guilherme Coutinho Kullmann Duarte, Daisy Crispim, Shiva Cerutti Wittée, Joana Raquel Nunes Lemos, Natalia Emerim Lemos, Mayara Souza de Oliveira, Melissa Daniele Alves, Eloísa Toscan Massignam, Tais Silveira Assmann, Felipe Mateus Pellenz   +9 more
wiley   +1 more source

Lipoprotein(a) apheresis restores coronary microcirculation in refractory angina

Revista Portuguesa de Cardiologia, 2022
Francesco Sbrana, Beatrice Dal Pino, Giovanni Donato Aquaro, Federico Bigazzi, Giuseppe Vergaro, Tiziana Sampietro   +5 more
doaj   +1 more source

Development of dyslipidemias in a cohort of Mexican adult patients with HIV/AIDS under highly active antiretroviral therapy

Mexican Journal of Medical Research ICSA
Dyslipidemias are comorbidities in seropositive patients under highly active antiretroviral therapy (HAART), which increase their risk of complications and reduce their life expectancy.
Guadalupe López-Rodríguez, Marcos Galván, Liliana Arias-Castelán   +2 more
doaj   +1 more source

Análise do perfil lipídico em escolares Lipid profile analysis in school children

Arquivos Brasileiros de Cardiologia, 2007
FUNDAMENTO: A aterosclerose coronariana (DAC) é a maior causa mortis do mundo, segundo a Organização Mundial de Saúde. O estudo INTERHEART mostrou que a dislipidemia é um dos maiores fatores de risco independente para o IAM.
Carlos Scherr, Cyntia Karla Magalhães, Waldir Malheiros   +2 more
doaj   +1 more source

Study of rare familial monogenic dyslipidemias [PDF]

, 2016
A dislipidemia é um distúrbio do perfil lipídico, seja por elevação ou diminuição de partículas lipídicas. O objetivo deste trabalho é fazer uma revisão dos casos com dislipidemia rara em estudo no Instituto Nacional de Saúde Doutor Ricardo Jorge ...
Alves, Ana Catarina, Bourbon, Mafalda, Duarte, Sequeira, Gaspar, Ana, Guerra, António, Lobarinhas, Goreti, Mansilha, Helena, Moldovan, Oana, Sequeira, Sílvia   +8 more
core