Results 111 to 120 of about 51,850 (252)

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 6, Page 729-747, September 2026.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins, Srinivas Kamath, Rachel H. Davis, Samuel P. Costello, Robert V. Bryant, Alice S. Day, Paul Joyce   +6 more
wiley   +1 more source

Prevalence of Dyspepsia in Rural Districts of Hamadan City in 2002

پزشکی بالینی ابن سینا, 2004
Dyspepsia is one of the most common entities referred to physicians by variable complaints including epigastric discomfort, upper abdominal fullness , heartburn, retching, nausea, vomiting and bloating.
Amir Majlesi, Khosro Mani Kashani, Mohammad Mahdi Karimi   +2 more
doaj  

Meta‐Analysis: Chronic Gastrointestinal Symptoms and Comorbidities in Hypermobile Ehlers–Danlos Syndrome and Hypermobility Spectrum Disorders

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 5, Page 574-589, September 2026.
This meta‐analysis reveals that a significant proportion of patients with hEDS/HSD experience gastrointestinal symptoms. The most prevalent symptoms include heartburn, abdominal pain, constipation, and nausea. There is a notable overlap of hEDS/HSD with chronic fatigue, DGBI, GERD, migraine, and orthostatic intolerance.
Dmitrii Kulin, Gerald Holtmann, Thomas Fairlie, Kyle Staller, Samuel Nurko, Laurie Keefer, Douglas A. Drossman, Michael P. Jones, Qasim Aziz, Ayesha Shah   +9 more
wiley   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Efficacy and Safety of Intensifying Once‐Weekly Insulin Icodec Treatment With Once‐Weekly Semaglutide in Adults With Type 2 Diabetes: A Single‐Arm, Open‐Label, Treat‐to‐Target, Phase 3b Trial (ONWARDS 8)

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8515-8522, September 2026.
ABSTRACT Aims To investigate the efficacy and safety of intensifying once‐weekly insulin icodec (icodec) with once‐weekly semaglutide in adults with type 2 diabetes (T2D). Materials and Methods ONWARDS 8 was a single‐arm, open‐label, treat‐to‐target, Phase 3b trial comprising a 26‐week icodec run‐in period and a 26‐week semaglutide intensification ...
Krzysztof Strojek, Andreas Liebl, Neha Narendra Mumbaikar, Stinne Byrholdt Søgaard, Sara Kehlet Watt, Athena Philis‐Tsimikas   +5 more
wiley   +1 more source

Antipredatory Strategies of Anurans: An Updated Conceptual Review

Ethology, Volume 132, Issue 9, Page 662-708, September 2026.
To unravel the evolutionary dynamics of predator–prey interactions, we propose an updated, three‐tiered classification of anuran antipredatory strategies. By mapping non‐behavioral, individual, and group defenses across five functional phases, this integrative framework introduces the concept of synergetic coupling.
Ubiratã Ferreira Souza, Lucas Rosado Mendonça, Carlos Jared, L. Felipe Toledo   +3 more
wiley   +1 more source

Safety and Efficacy of a Hydrolyzed Collagen Formulation (HYCOS) for Facial Skin Elasticity and Wrinkles: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Oral collagen supplements are widely marketed for improving skin aging parameters, however, high‐quality clinical evidence for multi‐ingredient formulations in Asian populations remains limited. Aims This study evaluated the safety and efficacy of a hydrolyzed collagen formulation (HYCOS) on facial skin parameters in healthy Thai ...
Sutthinee Wisutthathum, Preeyanuch Pimjuk, Nitina Yeesibsean, Katechan Jampachaisri, Panlop Chakkavittumrong, Warisara Pasri, Pichet Kittikun, Supaporn Tuanthai, Thanwarat Suebwongfag, Tanyarat Sutti, Jew Puay Tay, Anjana Fuangchan, Neti Waranuch   +12 more
wiley   +1 more source

After‐work unhealthy eating, work‐induced ego depletion and abusive supervision: The moderating role of narcissistic admiration and rivalry

Journal of Occupational and Organizational Psychology, Volume 99, Issue 3, September 2026.
Abstract Abusive supervision, a harmful pattern of leadership behaviour, has consistently been found to have negative effects in the workplace. Drawing on self‐regulation and the work‐home resources model, we investigate the daily antecedents of abusive supervision from the work (ego depletion) and nonwork (unhealthy eating) domains. We examine leaders'
Xiaoyu Gan, Anna Topakas, Kristin Hildenbrand, Kara Ng, Malcolm Patterson   +4 more
wiley   +1 more source

Dyspepsia

International Journal of Clinical Practice, 1953
openaire   +2 more sources

Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence‐Based Expert Review

International Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 852-879, August 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prevalent, heterogeneous inflammatory disease associated with significant morbidity. Systemic corticosteroids (SCS) are commonly prescribed for their anti‐inflammatory effects, but cumulative exposure carries risks, including metabolic, cardiovascular, and skeletal complications.
Andrew Thamboo, Deanna Gigliotti, Eugenio De Corso, Stella Lee, Benjamin S. Bleier, Christopher J. Chin, Marie‐Noelle Corriveau, Valerie Hox, Claire Hopkins, Peter H. Hwang, Arif Janjua, Ludger Klimek, Daniel Lee, John Lee, Amber Luong, Geoffrey Mortuaire, Joaquim Mullol, Zara M. Patel, John Scott, Doron Sommer, Leigh Sowerby, Marc Tewfik, Beatrice Voizard, Martin Wagenmannm, Sarah K. Wise, Jonathan Yip, Quirina Thompson, Martin Desrosiers, Yvonne Chan   +28 more
wiley   +1 more source