Results 91 to 100 of about 513,093 (363)

Difference between clinical and ultrasound screening of developmental hip abnormalities in neonatal period [PDF]

open access: yesMedicinski Glasnik, 2007
The development disorder of the hip (DDH) is the most common anomaly of the locomotors’ system and a permanently present problem in pediatric and orthopedic practice, because of its numerous consequences.
A. Brčić
doaj  

Dentin dysplasia type II: An exclusive report of two cases in siblings

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2017
Dentin dysplasia is a rare autosomal dominant disorder affecting dentin and resulting in early loss of teeth. Although dentin dysplasia type I is reported to have an incidence of 1 in 100,000, dentin dysplasia type II is considered to be an extremely ...
Deepak Daryani   +2 more
doaj   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

Proteomics Research on Gastric Intraepithelial Neoplasia

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To investigate the expression of differential proteins in the typical process of gastric intraepithelial neoplasia including normal gastric antrum mucosa, reactive hyperplasia, low-grade intraepithelial neoplasia, high-grade intraepithelial ...
GUAN Xiaoying, WANG Furong
doaj   +1 more source

Intramucosal Poorly Differentiated Adenocarcinomas Detected in a Patient with Long-Standing Ulcerative Colitis

open access: yesCase Reports in Oncology, 2020
We report a case of long-standing ulcerative colitis with intramucosal well- and poorly differentiated adenocarcinomas detected over a 6-month duration.
Junichi Zaitsu   +9 more
doaj   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Molecular Mechanisms and Clinical Aspects of Colitis-Associated Cancer in Ulcerative Colitis

open access: yesCells
Inflammatory bowel diseases have long been recognized as entities with a higher risk of colorectal cancer. An increasing amount of information has been published regarding ulcerative colitis-associated colorectal cancer and its unique mechanisms in ...
Jesus K. Yamamoto-Furusho   +1 more
doaj   +1 more source

Comparative study on the efficacy of tissue autofluorescence (visually enhanced lesion scope) and toluidine blue as a screening method in oral potentially malignant and malignant lesions

open access: yesJournal of Medical Sciences, 2017
Objective and Study Design: Early identification of high-risk disease could greatly reduce both mortality and morbidity due to oral cancer. Hence, screening of such lesions and their early detection could improve prognosis.
Hasan Ali Adil   +4 more
doaj   +1 more source

Is arrhythmogenic right ventricular cardiomyopathy a paediatric problem too? [PDF]

open access: yes, 2001
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart muscle disease that is often familial, characterized by arrhythmias of right ventricular origin, due to transmural fatty or fibrofatty replacement of atrophic myocardium. ARVC is usually
Basso, Cristina   +4 more
core  

Screening Relevance of Sessile Serrated Polyps [PDF]

open access: yes, 2019
Conventional adenomas have historically been considered to be the only screening-relevant colorectal cancer (CRC) precursor lesion. The prevailing paradigm was that most CRCs arise along the chromosomal instability pathway, where adenomas accumulate ...
Kahi, Charles J.
core   +1 more source

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