Results 91 to 100 of about 255,645 (319)

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

Optimizing ventilator support in severe bronchopulmonary dysplasia in the absence of conclusive evidence

Frontiers in Pediatrics, 2022
Audrey N. Miller, Audrey N. Miller, Matthew J. Kielt, Matthew J. Kielt, George T. El-Ferzli, George T. El-Ferzli, Leif D. Nelin, Leif D. Nelin, Edward G. Shepherd, Edward G. Shepherd   +9 more
doaj   +1 more source

Exploring vision transformers for classifying early Barrett's dysplasia in endoscopic images: A pilot study on white‐light and narrow‐band imaging

JGH Open
Background and Aim Various deep learning models, based on convolutional neural network (CNN), have been shown to improve the detection of early esophageal neoplasia in Barrett's esophagus.
Jin L Tan, Dileepa Pitawela, Mohamed A Chinnaratha, Andrawus Beany, Enrik J Aguila, Hsiang‐Ting Chen, Gustavo Carneiro, Rajvinder Singh   +7 more
doaj   +1 more source

Dysplasia Epiphysealis Hemimelica of The Trochlear Epiphysis [PDF]

, 1997
Dysplasia epiphysealis hemimelica is an uncommon disorder primarily involving the epiphyes of the lower extremities. We report imaging findings of a case of dysplasia epiphysealis hemimelica involving the trochlear epiphysis of the humerus.
Ito, Nobuyuki, Uetani, Masataka, Hashmi, Rashid, Hayashi, Kuniaki, Hayashi, Tomayoshi   +4 more
core  

Xstainer: A Novel Virtual Staining Tool Powered by Advanced Deep Learning Techniques

Advanced Intelligent Systems, EarlyView.
Xstainer is a deep learning–based virtual staining framework that converts hematoxylin and eosin‐stained whole slide images into multiple histochemical stains, including Masson's trichrome, Periodic acid‐Schiff, Jones methenamine silver, and Toluidine blue.
Fatma Nur Kinali, Derya Demir, Kutsev B. Ozyoruk, Yasin Almalioglu, Emre C. Kose, Drew F. K. Williamson, Gurdeniz Serin, G. Evren Keles, Banu S. Kumbaraci, Ceren Utku, Uguray P. Hacisalihoglu, Ilknur Turkmen, Figen Ozturk, Kayhan Basak, Yavuz Nuri Ertas, Mehmet Turan   +15 more
wiley   +1 more source

Mechanisms of Lung Injury in a Mouse Model of Bronchopulmonary Dysplasia

, 2009
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects preterm infants. Increased levels of inflammatory mediators in the amniotic fluid and in the lungs of preterm infants are associated with the development of BPD.
Hogmalm, Anna
core  

Mutations in LTBP3 cause acromicric dysplasia and geleophysic dysplasia

, 2016
Background Acromelic dysplasias are a group of disorders characterised by short stature, brachydactyly, limited joint extension and thickened skin and comprises acromicric dysplasia (AD), geleophysic dysplasia (GD), Myhre syndrome and Weill-Marchesani ...
Cormier-Daire, Valerie, Leo, Paul J., Duncan, Emma L., Keith, Patricia, Harris, Jessica E., Zankl, Andreas, Brown, Matthew A., Steer, Ruth, Nitschke, Patrick, Duncan, Emma L, Brown, Matthew A, Goff, Carine Le, Bole-Feysot, Christine, Le Goff, Carine, Kielty, Cay, McInerney-Leo, Aideen M., Kenna, Tony J.   +16 more
core   +1 more source

Complex roles of TGF-β signaling pathways in lung development and bronchopulmonary dysplasia

, 2023
As survival of extremely preterm infants continues to improve, there is also an associated increase in bronchopulmonary dysplasia (BPD), one of the most significant complications of preterm birth. BPD development is multifactorial resulting from exposure
Sharkey, Don, Bhatt, Jayesh, Calthorpe, Rebecca J., Poulter, Caroline, Jenkins, Gisli, Tatler, Amanda L., Smyth, Alan R.   +6 more
core   +1 more source

Therapeutic Silencing of Tmprss6 Reduces Iron‐Induced Inflammation and Prolongs Survival in MDS Mice

American Journal of Hematology, EarlyView.
ABSTRACT Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders characterized by ineffective hematopoiesis, cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Despite advances in supportive and targeted therapies, disease‐modifying interventions remain limited.
Shahla Vilcassim, Nuttanan Pholngam, Rattanawan Thubthed, Tiwaporn Nualkaew, Saovaros Svasti, Pornthip Chaichompoo, Kai Kysenius, Peter J. Crouch, Sibylle Dames, Mona Eisermann, Alberto Martinez, Ute Schaeper, Jim Vadolas, George Grigoriadis   +13 more
wiley   +1 more source

Renal artery stenosis-when to screen, what to stent? [PDF]

, 2014
Renal artery stensosis (RAS) continues to be a problem for clinicians, with no clear consensus on how to investigate and assess the clinical significance of stenotic lesions and manage the findings.
Thomas M. MacDonald, John G. Houston, Jennings, Claudine G., Bell, Samira; id_orcid, Alison Severn, Isla S. Mackenzie, Mackenzie, Isla S.; id_orcid, MacDonald, Thomas M., Severn, Alison, Samira Bell, Claudine G. Jennings, Houston, John G.   +11 more
core   +1 more source