Results 91 to 100 of about 333,388 (343)

Withdrawal of Mechanical Ventilation in the ICUTake-Home Points

CHEST Critical Care
Background: More than 1 in 5 Americans die in ICUs, 50% of whom undergo palliative withdrawal of mechanical ventilation (WMV). Little is known about their experiences or best practices to minimize any suffering they may experience. Research Question: How
Corey R. Fehnel, MD, MPH, Zara Cooper, MD, MPH, Margaret Campbell, RN, PhD, Daniel Habtemariam, MSc, MPH, Thomas G. Travison, PhD, Daniel Forsman, MD, Richard M. Schwartzstein, MD, Douglas B. White, MD, MAS, Susan L. Mitchell, MD, MPH, Andrea C. Norton, BM, John Jehle, NP, Lorna Caffery, RN, Carter Glenn, RN, Joanna Anderson, RN, MSNt   +13 more
doaj   +1 more source

Association of Abatacept With Lower Mortality Risk Compared to Rituximab in Rheumatoid Arthritis–Associated Interstitial Lung Disease: An Emulated Target Trial

Arthritis &Rheumatology, EarlyView.
Objective The optimal treatment strategy for rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) remains uncertain, and direct comparative data between biologics are limited. This study aimed to evaluate the effectiveness and safety of abatacept compared with rituximab in patients with RA‐ILD.
Po‐Cheng Shih, Shiow‐Ing Wang, Qing‐Wen Wang, James Cheng Chung Wei   +3 more
wiley   +1 more source

Use of Echocardiography Under Hypoxic Stress Without Exercise to Assess Right to Left Shunting

Journal of Cardiovascular Development and Disease
Acute exposure to hypoxia will induce right ventricular (RV) hemodynamic changes and may increase the degree of right-to-left shunting, which can contribute to dyspnea at altitude.
Cecilia Villa Etchegoyen, Rachel E. Wraith, Lisa S. Brown, Karen K. Breznak, Rohit Mital, Steven J. Lester, Chadi Ayoub, Said Alsidawi, Justin N. Shipman, Juan M. Farina, Reza Arsanjani, Jan Stepanek   +11 more
doaj   +1 more source

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella, Triposkiadis, Filippos   +1 more
core   +2 more sources

Performance of an Idiopathic Pulmonary Fibrosis–Derived Multibiomarker Panel for Rheumatoid Arthritis–Associated Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective To assess whether a panel of peripheral blood biomarkers associated with idiopathic pulmonary fibrosis (IPF) is also associated with interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) using three independent cohorts. Methods We first assessed the association of a panel of IPF‐associated biomarkers with prevalent ILD ...
Brent A. Luedders, Daniel Kass, Joshua F. Baker, Michael J. Duryee, Yangyuna Yang, Punyasha Roul, Halie Frideres, Katherine D. Wysham, Paul A. Monach, Andreas Reimold, Gail S. Kerr, Gary Kunkel, Grant W. Cannon, Scott M. Matson, Jill A. Poole, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England, Dana P. Ascherman   +18 more
wiley   +1 more source

Cosmetic Talc-Related Pulmonary Granulomatosis. [PDF]

, 2017
Inhalation of cosmetic talc can lead to pulmonary foreign-body granulomatosis, though fewer than 10 cases of inhaled cosmetic talc-related pulmonary granulomatosis have been reported in adults.
Adams, Jason Y, Jasuja, Sonia, Kuhn, Brooks T, Schivo, Michael   +3 more
core   +1 more source

Impact of evolving treatment patterns on interstitial lung disease progression in systemic sclerosis using the EUSTAR database

Arthritis &Rheumatology, Accepted Article.
Background The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasing immunosuppressive (IST) and anti‐fibrotic therapies available. However, their real‐world use remains unclear. Objectives To analyze treatment trends and the effect of IST and anti‐fibrotic therapies on ILD progression ...
Corrado Campochiaro, Marie‐Elise Truchetet, Madelon Vonk, Giacomo De Luca, Giovanna Cuomo, Lidia P. Ananieva, Eric Hachulla, Vanessa Smith, Ana Maria Gheorghiu, Radim Becvar, Patricia Carreira, Nicolas Hunzelmann, Daniel E. Furst, Vera Ortiz‐Santamaria, Francesco Del Galdo, Marco Matucci‐Cerinic, Anna‐Maria Hoffmann‐Vold, EUSTAR collaborators   +17 more
wiley   +1 more source

AN UNUSUAL FORM OF SILICOSIS IN A STONE-CUTTER [PDF]

Acta Medica Iranica, 2007
Silicon dioxide or silica is the earth’s most abundant mineral. The primary pulmonary illness attributable to silica exposure is silicosis, which is observed in three forms: classic, accelerated and acute. A case of silicosis is presented in this article
S. A. Sharifian, A. H. Mehrparvar S. Mohammadi   +1 more
doaj  

Hypersensitivity Pneumonitis Associated with Environmental Mycobacteria [PDF]

, 2005
A previously healthy man working as a machine operator in an automotive factory developed respiratory symptoms. Medical evaluation showed abnormal pulmonary function tests, a lung biopsy showed hypersensitivity pneumonitis, and his illness was traced to ...
Akshay Sood, Anonymous, CDC, Donald Milton, Mery A, Michael Kallay, William Beckett, Zhengfa Zuo   +7 more
core   +2 more sources

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source