Results 51 to 60 of about 59,501 (281)

Cervical dystonia: A disorder of the midbrain network for covert attentional orienting [PDF]

, 2014
While the pathogenesis of cervical dystonia remains unknown, recent animal and clinical experimental studies have indicated its probable mechanisms. Abnormal temporal discrimination is a mediational endophenotype of cervical dystonia and informs new ...
O\u27Riordan, Sean, Kimmich, Okka, Williams, Laura, Hutchinson, Michael, Isa, Tadashi, Molloy, Anna, O'Riordan, Sean, et al., Okka Kimmich, Fiona Molloy, Tadashi Isa, Tim Lynch, Richard B. Reilly, Laura Williams, Daniel G. Healy, Cathal Walsh, Michael Hutchinson, Sean O’Riordan, Anna Molloy, John Butler, Helena Moore, Richard Walsh   +21 more
core   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Deconstructing motor and non-motor aspects of dystonia with neuroimaging

Dystonia, 2023
Dystonia, the third most common movement disorder, is clinically characterized by involuntary muscle contractions leading to abnormal, patterned movements and postures that are often activated or worsened by initiation of movement.
Abhimanyu Mahajan
doaj   +1 more source

Genetic Etiologies of Dystonia with Anarthria/Aphonia. [PDF]

Mov Disord Clin Pract
Abstract Background Dystonia with anarthria and/or aphonia (DAnAp) represents a distinctive phenotype manifesting across lifespan. Frequently associated with genetic disorders, early recognition is critical for diagnosis and management. Objectives To provide practical recommendations for the clinical evaluation of patients with DAnAp, enhancing ...
Ménétrey A, Rayco E, Abarghouei ME, Fox SH, Lang AE, Ibrahim GM, Gorodetsky C, Ganos C.   +7 more
europepmc   +2 more sources

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Behavioral signature of trihexyphenidyl in the TOR1A (DYT1) knockin mouse model of dystonia

Dystonia
Dystonia is a neurological disorder characterized by involuntary repetitive movements and abnormal postures. Animal models have played a pivotal role in studying the pathophysiology of dystonia.
Ahmad Abdal Qader, Yuping Donsante, Jeffrey E. Markowitz, H. A. Jinnah, H. A. Jinnah, Chethan Pandarinath, Chethan Pandarinath, Ellen J. Hess, Ellen J. Hess   +8 more
doaj   +1 more source

Immobilization dystonia

Journal of the Neurological Sciences, 2002
The mechanisms underlying dystonia after injury are unclear. Pain has been implicated as an important factor. We report four patients who exhibited segmental dystonia following removal of a cast, only two of whom experienced pain during casting.
The Neurology Service, Department of Neurology, University of Florida College of Medicine S. Newell Drive, L3-100, Gainesville, FL 32610-0236, USA ( host institution ), Okun, Michael S ( author ), Nadeau, Stephen E ( author ), Rossi, Fabian ( author ), Triggs, William J ( author )   +4 more
openaire   +3 more sources

Idiopathic Non-Task-Specific Upper Limb Dystonia, a Neglected Form of Dystonia

, 2020
Objective: The objective of this study was to describe the clinical and demographic features of idiopathic non-task-specific upper limb dystonia compared with the task-specific form.
Albanese A., Scaglione C., Bertolasi L., Ceravolo R., Defazio G., Lalli S., Pisani A., Marchese R., Esposito M., Ercoli T., Eleopra R., Barone P., Fabbrini G., Mascia M. M., Italian Dystonia Registry, Liguori R., Altavista M. C., Bentivoglio A. R., Ferrazzano G., Pellicciari R., Bono F., Girlanda P., Erro R., Berardelli A., Paolo Girlanda, Altavista, Maria Concetta, Roberto Eleopra, Girlanda, Paolo, Marcello Mario Mascia, Roberta Pellicciari, Esposito, Marcello, Fabbrini, Giovanni, Alfredo Berardelli, Roberto Ceravolo, Marchese, Roberta, Pellicciari, Roberta, Marcello Esposito, Liguori, Rocco, Ceravolo, Roberto, Scaglione, Cesa, Bertolasi, Laura, Albanese, Alberto, Defazio, Giovanni, Eleopra, Roberto, Tommaso Ercoli, Rocco Liguori, Roberta Marchese, null, null, Laura Bertolasi, Bentivoglio, Anna Rita, Anna Rita Bentivoglio, Erro, Roberto, Lalli, Stefania, Giovanni Defazio, Alberto Albanese, Barone, Paolo, Giovanni Fabbrini, Cesa Scaglione, Antonio Pisani, Roberto Erro, Paolo Barone, Berardelli, Alfredo, Mascia, Marcello Mario, Pisani, Antonio, Maria Concetta Altavista, Stefania Lalli, Ercoli, Tommaso, Bono, Francesco, Francesco Bono   +68 more
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source