Results 121 to 130 of about 28,350 (246)
International audienceMyoblast transplantation has been considered a potential treatment for some muscular disorders. It has proven very successful, however, only in immunodeficient or immunosuppressed mice.
I Kinoshita +9 more
core +1 more source
Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley +1 more source
Abstract Background Mutations in DMD affect not only muscles but also the brain. Cases of schizophrenia with DMD mutations have been described previously. Although female dystrophinopathy often has a milder phenotype, some affected females also have intellectual disabilities and psychiatric disorders.
Shusei Arafuka +15 more
wiley +1 more source
Ryanodine Receptor Ca2+ Leak‐Induced Redistribution of Ca2+ in Dystrophic mdx Mouse Muscle
ABSTRACT Aim The dystrophic mdx mouse is a widely used model of Duchenne muscular dystrophy. Altered Ca2+ handling is a key feature, including increased Ca2+ leak through the ryanodine receptor (RyR1's), the primary Ca2+ release channel in skeletal muscle. Such leak has important downstream consequences for intracellular Ca2+ homeostasis.
Rhayanna B. Gaglianone +5 more
wiley +1 more source
Overview of dystrophin antibodies.
Overview of dystrophin antibodies.
Anneke A. Janson (5089481) +4 more
core +1 more source
In this retrospective single‐center study of 1018 routine Holter ECG recordings from 167 patients with Duchenne muscular dystrophy, nonsustained ventricular tachycardia and frequent premature ventricular complexes were common. Reduced left ventricular function was the strongest associated factor, supporting regular Holter monitoring for patients at ...
Ryo Sugiyama +6 more
wiley +1 more source
The dystrophin C-terminal domains and interactions with the dystrophin-associated protein complex.
Dystrophin plays an important role in skeletal muscle by linking the cytoskeleton and the extracellular matrix. The amino-terminus of dystrophin binds to actin, while the carboxy-terminus associates with the dystrophin-associated protein (DAP) complex ...
Rafael, Jill Amy
core
Abstract This study investigated whether performing a translatable murine model of concurrent training after tumour induction affects adaptations in juvenile male and female tumour‐bearing mice. Male and female Balb/c mice were injected bilaterally with colon‐26 adenocarcinoma (C26) cells or PBS at 8 weeks of age.
Stavroula Tsitkanou +10 more
wiley +1 more source
Dystrophin expression during skeletal myogenesis
The factors that regulate dystrophin accumulation, and its association with other proteins in culture, are largely unknown. In this study I have examined the effects of chemical agents on dystrophin accumulation in culture, as well as determined whether ...
Ajdukovic, Boris
core
Dystrophin gene regulation in muscle
grantor: University of TorontoThe identification and characterization of the muscle-promoter and a muscle-specific enhancer within intron I has led to advances in our understanding of dystrophin gene regulation in muscle. However, the sequences
Bestard, Jennifer
core +1 more source

