Results 121 to 130 of about 28,350 (246)

Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin.

open access: yes, 1995
International audienceMyoblast transplantation has been considered a potential treatment for some muscular disorders. It has proven very successful, however, only in immunodeficient or immunosuppressed mice.
I Kinoshita   +9 more
core   +1 more source

Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley   +1 more source

Dystrophinopathy with a DMD exon 49–50 deletion in a female patient who developed schizophrenia: An autopsy case

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Abstract Background Mutations in DMD affect not only muscles but also the brain. Cases of schizophrenia with DMD mutations have been described previously. Although female dystrophinopathy often has a milder phenotype, some affected females also have intellectual disabilities and psychiatric disorders.
Shusei Arafuka   +15 more
wiley   +1 more source

Ryanodine Receptor Ca2+ Leak‐Induced Redistribution of Ca2+ in Dystrophic mdx Mouse Muscle

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The dystrophic mdx mouse is a widely used model of Duchenne muscular dystrophy. Altered Ca2+ handling is a key feature, including increased Ca2+ leak through the ryanodine receptor (RyR1's), the primary Ca2+ release channel in skeletal muscle. Such leak has important downstream consequences for intracellular Ca2+ homeostasis.
Rhayanna B. Gaglianone   +5 more
wiley   +1 more source

Overview of dystrophin antibodies.

open access: yes, 2018
Overview of dystrophin antibodies.
Anneke A. Janson (5089481)   +4 more
core   +1 more source

Prevalence and Characteristics of Cardiac Arrhythmia in Duchenne Muscular Dystrophy: A Retrospective, Single‐Center Holter Electrocardiographic Monitoring Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 6, June 2026.
In this retrospective single‐center study of 1018 routine Holter ECG recordings from 167 patients with Duchenne muscular dystrophy, nonsustained ventricular tachycardia and frequent premature ventricular complexes were common. Reduced left ventricular function was the strongest associated factor, supporting regular Holter monitoring for patients at ...
Ryo Sugiyama   +6 more
wiley   +1 more source

The dystrophin C-terminal domains and interactions with the dystrophin-associated protein complex.

open access: yes, 1996
Dystrophin plays an important role in skeletal muscle by linking the cytoskeleton and the extracellular matrix. The amino-terminus of dystrophin binds to actin, while the carboxy-terminus associates with the dystrophin-associated protein (DAP) complex ...
Rafael, Jill Amy
core  

Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice

open access: yesExperimental Physiology, Volume 111, Issue 6, Page 3039-3054, 1 June 2026.
Abstract This study investigated whether performing a translatable murine model of concurrent training after tumour induction affects adaptations in juvenile male and female tumour‐bearing mice. Male and female Balb/c mice were injected bilaterally with colon‐26 adenocarcinoma (C26) cells or PBS at 8 weeks of age.
Stavroula Tsitkanou   +10 more
wiley   +1 more source

Dystrophin expression during skeletal myogenesis

open access: yes, 1992
The factors that regulate dystrophin accumulation, and its association with other proteins in culture, are largely unknown. In this study I have examined the effects of chemical agents on dystrophin accumulation in culture, as well as determined whether ...
Ajdukovic, Boris
core  

Dystrophin gene regulation in muscle

open access: yes, 2000
grantor: University of TorontoThe identification and characterization of the muscle-promoter and a muscle-specific enhancer within intron I has led to advances in our understanding of dystrophin gene regulation in muscle. However, the sequences
Bestard, Jennifer
core   +1 more source

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