Results 181 to 190 of about 56,717 (273)

Stepwise Diagnostic Strategy Integrating Long-Read Sequencing for the Interpretation of Phenotype-Genotype Discordance in Dystrophinopathy. [PDF]

Appl Clin Genet
Yuan Q, Liu C, Lu Y, Han X, Wang Z, Yuan Y, Xie Z.   +6 more
europepmc   +1 more source

Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase

Science Translational Medicine, 2016
S. Reilly, Xing Liu, R. Carnicer, A. Recalde, Anna Muszkiewicz, R. Jayaram, M. Carena, R. Wijesurendra, Matilde Stefanini, N. Surdo, O. Lomas, C. Ratnatunga, R. Sayeed, G. Krasopoulos, T. Rajakumar, A. Bueno-Orovio, S. Verheule, T. Fulga, B. Rodríguez, U. Schotten, B. Casadei   +20 more
semanticscholar   +1 more source

Improving angiogenesis ameliorates the efficacy of ASO-based exon skipping for the treatment of Duchenne muscular dystrophy. [PDF]

Mol Ther Nucleic Acids
Blitek M, Gastaldi C, Doisy M, Le Coz O, David M, Phongsavanh X, Ben Aicha S, Garcia L, Rotini A, Pagès G, Goyenvalle A.   +10 more
europepmc   +1 more source

Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy

Human Genetics, 2016
J. Robinson-Hamm, C. Gersbach
semanticscholar   +1 more source

Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior. [PDF]

Commun Biol
Karuppasamy M, English KG, Conner JR, Rorrer SN, Lopez MA, Crossman DK, Paul JR, Gutierrez-Monreal MA, Gamble KL, Esser KA, Widrick JJ, Kunkel LM, Alexander MS.   +12 more
europepmc   +1 more source

Dystrophin contains multiple independent membrane-binding domains.

Human Molecular Genetics, 2016
Junling Zhao, Kasun Kodippili, Y. Yue, Chady H. Hakim, L. Wasala, Xiufang Pan, Keqing Zhang, N. N. Yang, D. Duan, Yi Lai   +9 more
semanticscholar   +1 more source

The Promise and Pitfalls of AAV-Mediated Gene Therapy for Duchenne Muscular Dystrophy. [PDF]

Curr Issues Mol Biol
Kurshakova EV, Levchenko OA, Smirnikhina SA, Lavrov AV.   +3 more
europepmc   +1 more source

Age-related Differences in Dystrophin: Impact on Force Transfer Proteins, Membrane Integrity, and Neuromuscular Junction Stability

The journals of gerontology. Series A, Biological sciences and medical sciences, 2016
David C. Hughes, George R. Marcotte, A. Marshall, Daniel W D West, Leslie M. Baehr, M. Wallace, Perrie M Saleh, S. Bodine, K. Baar   +8 more
semanticscholar   +1 more source

Brain Matters in Duchenne Muscular Dystrophy: DMD Mutation Sites and Their Association with Neurological Comorbidities Through Isoform Impairment. [PDF]

Genes (Basel)
Barbarii T, Tudorache RA, Craiu D, Neagu E, Brinduse LA, Burloiu CM, Iliescu CM, Budisteanu M, Minciu I, Barca DG, Sandu C, Tarta-Arsene O, Pomeran C, Motoescu C, Dica A, Anghelescu C, Surlica D, Toma AI, Butoianu N.   +18 more
europepmc   +1 more source

Nicorandil, a Nitric Oxide Donor and ATP-Sensitive Potassium Channel Opener, Protects Against Dystrophin-Deficient Cardiomyopathy

Journal of Cardiovascular Pharmacology and Therapeutics, 2016
M. Z. Afzal, M. Reiter, Courtney Gastonguay, Jered McGivern, X. Guan, Z. Ge, D. Mack, M. Childers, A. Ebert, J. Strande   +9 more
semanticscholar   +1 more source