Results 91 to 100 of about 40,039,274 (254)
Thermal free energy of large N-f QED in 2+1 dimensions from weak to strong coupling [PDF]
, 2019 In 2 + 1 dimensions, QED becomes exactly solvable for all values of the fermion charge e in the limit of many fermions N-f >> 1. We present results for the free energy density at finite temperature T to next-to-leading-order in large N-f.
Säppi, Matias, Romatschke, Paul
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
, 2016 The stereoselective synthesis of the maitotoxin C′D′E′F′-ring system having a side chain has been accomplished through a convergent strategy. The key reactions include Horner-Wadsworth-Emmons coupling of the C′D′E′-ring and the side chain and subsequent ...
Tadashi Nakata (2103187) +3 more
core +2 more sources
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Earth, Planets and SpaceElectrodynamic coupling between the ionospheric E and F regions is widely recognized as the underlying mechanism for generating medium-scale traveling ionospheric disturbances (MSTIDs) during nighttime at midlatitudes.
Weizheng Fu +4 more
doaj +1 more source
MetalsThe microstructure of Ti-Al-Si coatings prepared by direct laser deposition (DLD) requires further refinement and homogenization to enhance coating performance.
Yu Li +4 more
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Spin−Spin Coupling across Intermolecular F−Cl···N Halogen Bonds
, 2016 Ab initio EOM-CCSD calculations have been performed to determine one- and two-bond spin−spin coupling constants 1J(F−Cl), 1XJ(Cl−N), and 2XJ(F−N) across F−Cl···N halogen bonds in complexes with F−Cl as the Lewis acid and N2, FCN, HCN, (CH3)CN, LiCN, Z ...
José Elguero (1391101) +2 more
core +2 more sources