Results 91 to 100 of about 534,393 (266)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

A slot antenna array with low mutual coupling for use on small mobile terminals [PDF]

, 2011
In order to take full advantage of the benefits to be obtained by using MIMO techniques for mobile communications, it is necessary to use an antenna array which is both compact and also has low mutual coupling between ports.
Paul, DL, Dominique L. Paul, Sema Dumanli, Dumanli, S, Railton, CJ, Chris J. Railton   +5 more
core   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

DelayTOT and its subcomponents: a new approach for the electromechanical delay partitioning before and after a fatiguing protocol during electrically-evoked contractions

, 2013
Aim: DelayTOT is the time lag between the onset of the electrical stimulation (Stim) and the force (F) development. During this time frame the following several mechanisms take place to transduce the electrical pulse into a mechanical events: i) the ...
S. Rampichini, E. Cè, F. Esposito, E. Limonta, A. Veicsteinas   +4 more
core  

Large long-range F-F indirect spin-spin coupling constants. Prediction of measurable F-F couplings over a few nanometers [PDF]

, 2004
Large long-range indirect nuclear spin coupling constants are of great interest for quantum computers. But they are rarely observed and are usually considered very small, unless the coupled nuclear spins are proximate in space.
Provasi, Patricio F., Sauer, Stephan P. A., Aucar, Gustavo Adolfo, Aucar, Gustavo A., Provasi, Patricio Federico   +4 more
core   +1 more source

rafaelcastanha/Academic-Genealogy-Bibliographic-Coupling: Academic Genealogy with Bibliographic Coupling

, 2022
bibliographic coupling between advisor and advisee Calcula a intensidade de acoplamento bibliográfico entre orientador e orientandos O corpus representa a lista de referencias entre orientador e seus orientandos A lista de referencia citada do orientador
Rafael Gutierres Castanha
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Performance of the double-thin-shell approach for studying nighttime medium-scale traveling ionospheric disturbances using two dense GNSS observation networks in Japan

Earth, Planets and Space
Electrodynamic coupling between the ionospheric E and F regions is widely recognized as the underlying mechanism for generating medium-scale traveling ionospheric disturbances (MSTIDs) during nighttime at midlatitudes.
Weizheng Fu, Yuichi Otsuka, Atsuki Shinbori, Michi Nishioka, Septi Perwitasari   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Solidification Behavior and Fine Grain Control of Ti-Al-Si Coating by Electrostatic Field Assisted Direct Laser Deposition

Metals
The microstructure of Ti-Al-Si coatings prepared by direct laser deposition (DLD) requires further refinement and homogenization to enhance coating performance.
Yu Li, Xueting Chen, Yinglong Liang, Shuai Zhang, Guili Yin   +4 more
doaj   +1 more source