Results 91 to 100 of about 18,651,759 (343)
PLoS ONE, 2011 The Cas scaffolding proteins (NEDD9/HEF1/CAS-L, BCAR1/p130Cas, EFSSIN, and HEPL/CASS4) regulate cell migration, division and survival, and are often deregulated in cancer. High BCAR1 expression is linked to poor prognosis in breast cancer patients, while upregulation of NEDD9 contributes to the metastatic behavior of melanoma and glioblastoma cells ...
Nadezhda Tikhmyanova, Erica A Golemis
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Advanced Functional Materials, EarlyView.Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni +8 more
wiley +1 more source
JCI Insight, 2023 Metastatic progression of epithelial cancers can be associated with epithelial-mesenchymal transition (EMT) including transcriptional inhibition of E-cadherin (CDH1) expression.
Kuppusamy Balamurugan +12 more
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Prognostic significance of E-cadherin and N-cadherin expression in Gliomas
BMC Cancer, 2017 Epithelial-mesenchymal transition (EMT), principally involving an E-cadherin to N-cadherin shift, linked to tumor invasion or metastasis, and therapeutic resistance in various human cancer.
Myung-Giun Noh +9 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Distribution of E- and N-cadherin in subgroups of non-functioning pituitary neuroendocrine tumours [PDF]
, 2022 Kristin Astrid Øystese +4 more
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E-cadherin: gatekeeper of airway mucosa and allergic sensitization
Trends in Immunology, 2011 The airway epithelium plays a role in immune regulation during environmental challenge, which is intertwined with its barrier function and capacity to limit submucosal access of environmental factors. In asthma, mucosal barrier function is often compromised, with disrupted expression of the adhesion molecule E-cadherin.
Nawijn, Martijn C +4 more
openaire +2 more sources
Roles for E-cadherin cell surface regulation in cancer
Molecular Biology of the Cell, 2016 Loss of E-cadherin expression often occurs in tumors, but many metastases retain E-cadherin. Regulation of the adhesive activity of E-cadherin at the cell surface is important for metastasis of mammary tumor cells, and cancer-associated missense ...
Y. Petrova, L. Schecterson, B. Gumbiner
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier +7 more
wiley +1 more source
Data in Brief, 2018 This article contains data related to the research article entitled, “A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices” (Rogers et. al., 2018) [1].
Crystal D. Rogers
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