Results 151 to 160 of about 174,214 (265)

The E-cadherin-Wnt-mir-994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell Maintenance. [PDF]

Cell Prolif
Tu R, Yau HL, Deng R, Webb SE, Chen S, Ni J, Xie T.   +6 more
europepmc   +1 more source

Redefining the Role of Splenectomy in Scirrhous Gastric Cancer: Toward a Selective Multimodal Strategy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Scirrhous gastric cancer, characterized by diffuse infiltration and a high propensity for peritoneal dissemination, remains one of the most aggressive subtypes of gastric cancer. Despite a relatively high incidence of splenic hilar lymph node (No. 10) metastasis, the oncologic benefit of splenectomy remains controversial, while its association
Tsutomu Hayashi, Takaki Yoshikawa
wiley   +1 more source

De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance. [PDF]

Nat Commun
Häkkinen HM, Batet M, Bianchi LF, Jiménez-Delgado S, Pezzano F, Wieser S, Ciampa L, Hoijman E, Vibe C, Wijma S, Ruprecht V.   +10 more
europepmc   +1 more source

ViTAMIn‐O: Democratizing Computer Vision‐Based Machine Learning for Stem Cell Research

Advanced Intelligent Systems, EarlyView.
This study introduces a fully open generalist computer vision model for predicting the differentiation outcomes of stem cell‐based model systems, together with its code‐free deployment platform, ColabViTAMIn‐O. It is benchmarked against various architectures, datasets, and training protocols.
Ferhat Hamurcu, Markus Breunig, Arpad Varga, Bianka Bosch, Jessica Lindenmayer, Anjan T. Kanakappady, Kevin Achberger, Natalia Pashkovskaia, Alexander Kleger, Stefan Liebau, Stefanie Klingenstein, Moritz Klingenstein   +11 more
wiley   +1 more source

[Retracted] Reduced expression levels of the death-associated protein kinase and E-cadherin are correlated with the development of esophageal squamous cell carcinoma. [PDF]

Exp Ther Med
Zhai J, Yang X, Zhang Y, Qi Q, Hu J, Wang Q.   +5 more
europepmc   +1 more source

Deep Learning Classification of Pancreatic Cancer Cells Over a Progression of Epithelial to Mesenchymal States by Deformability Cytometry Under Microfluidic Viscoelastic Flows

Advanced Intelligent Systems, EarlyView.
Cancer cells progressively spread over intermediate epithelial‐to‐mesenchymal transition states that cause nuclear enlargement and circular redistribution of filamentous vimentin are classified by deformability cytometry coupled to a multi‐region deep learning model with convolutional feature extraction and attention‐based regional aggregation.
Javad Jarmoshti, Hanyuan Gao, Negin Zeinali, Abdullah‐Bin Siddique, Sara J. Adair, Todd W. Bauer, Matthew J. Lazzara, Xiaoxuan Yang, Nathan S. Swami   +8 more
wiley   +1 more source

E-cadherin inactivation shapes tumor microenvironment specificities in invasive lobular breast cancer. [PDF]

Nat Commun
Djerroudi L, Mhaidly R, Kieffer Y, Damei I, Croizer H, Selvarasa V, Gentric G, Fuhrmann L, Goncalves A, Caly M, Richardot C, Leclere R, Laas E, Malhaire C, Cao K, Houthuijzen JM, Kloosterman P, Jonkers J, Benoist C, Renault V, Bidard FC, Vincent-Salomon A, Mechta-Grigoriou F.   +22 more
europepmc   +1 more source

A Novel Homozygous Nonsense Variant in DCHS1 in a Brazilian Patient With Van Maldergem Syndrome Type 1: Clinical Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Van Maldergem syndrome (VMLDS) is an ultra‐rare autosomal recessive disorder characterized by craniofacial dysmorphism, intellectual disability, hypotonia, skeletal anomalies, and feeding difficulties. It is caused by biallelic variants in DCHS1 or FAT4 genes.
Gabriela Roldão Correia‐Costa, Bruna Fagundes Rodrigues Alaite, Vera Lúcia Gil‐da‐Silva‐Lopes, Carlos Eduardo Steiner, Társis Paiva Vieira   +4 more
wiley   +1 more source

Overexpression of TAZ is associated with downregulation of E-cadherin and indicates poor prognosis in gastric cancer: a clinicopathological study. [PDF]

J Gastrointest Oncol
Luo X, Tu Y, Wu D, Cai X, Li W, Yang S.
europepmc   +1 more source

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source