Results 251 to 260 of about 18,651,759 (343)

E-cadherin-mediated force transduction signals regulate global cell mechanics

Journal of Cell Science, 2016
Ismaeel Muhamed, Jun Wu, Poonam Sehgal, Xinyu Kong, A. Tajik, Ning Wang, D. Leckband   +6 more
semanticscholar   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

A Longitudinal Study of E-Cadherin and Beta-Catenin in Progression of Oral Epithelial Dysplasia. [PDF]

J Oral Pathol Med
Yim IS, Zhang L, Rock LD, Rosin MP, Lin I, Laronde DM.   +5 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Targeting GRPR for sex hormone-dependent cancer after loss of E-cadherin. [PDF]

Nature
Raymond JH, Aktary Z, Pouteaux M, Petit V, Luciani F, Wehbe M, Gizzi P, Bourban C, Decaudin D, Nemati F, Martianov I, Davidson I, Tomasetto CL, White RM, Mahuteau-Betzer F, Vergier B, Larue L, Delmas V.   +17 more
europepmc   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Clinical importance of E-cadherin deficiency in resectable gastric cancer: A nested case-control study. [PDF]

Oncol Lett
Zheng C, Dai M, Wang D, Liu X, Xiang Z, Xu A, Chen P, Wu F, Yuan Y, Ji S, Gu L.   +10 more
europepmc   +1 more source

ADAMTS9‐AS2 Disrupts Docetaxel‐Resistance in Castration‐Resistant Prostate Cancer via Stemness Suppression and Ferroptosis Induction

Advanced Science, EarlyView.
This study uncovered a dual‐track mechanism by which ADAMTS9‐AS2 overcame chemoresistance in CRPC: suppressing cancer stemness through the FOXF2/TGF‐β2 pathway, and triggering ferroptosis via competitive SLC7A11 sequestration. Polymeric materials co‐targeting these vulnerabilities further boost docetaxel sensitivity, highlighting a compelling strategy ...
Ji Liu, Yan Gao, Yadong Guo, Junfeng Zhang, Wentao Zhang, Zhuoran Gu, Haotian Chen, Chengqi Jin, Peng Luo, Shiyu Mao, Yajuan Hao, Shuo Shi, Xudong Yao   +12 more
wiley   +1 more source

PCSK9 promotes progression of anaplastic thyroid cancer through E-cadherin endocytosis. [PDF]

Cell Death Dis
Zhang Y, Su W, Ji X, Yang Z, Guan Q, Pang Y, Zhong L, Wang Y, Xiang J.   +8 more
europepmc   +1 more source