Results 111 to 120 of about 31,819,981 (309)
Semantic frameworks for e-government
This paper explains how semantic frameworks can be used to support successful e-Government initiatives by connecting system design to a shared understanding of interactions and processes. It shows how metadata standards and repositories can be used to establish and maintain such an understanding, and how they can be used in the automatic generation and
Charles Crichton +4 more
openaire +4 more sources
GOVERNANCE ON THE INTERNET. MEASURING THE PERFORMANCES OF E-GOVERNANCE IN BUCHAREST MUNICIPALITIES [PDF]
This paper analyzes the electronic governance and how it’s functioning in Romania. Being part of a larger institutional reform process, the electronic governance represents a new approach of the relation between Government and the citizen, with the ...
ANDREI ELVADEANU
doaj
Designing a foresight model of electronic governance with organizational transparency of Bank Saderat managers of Tehran province [PDF]
The purpose of this research is the relationship between e-governance foresight and the organizational transparency of managers (case study: Saderat Bank of Tehran province).
Manijeh Barazideh +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
The article explores the theoretical and methodological foundations of digital governance as a strategic direction for the transformation of the public administration system in the context of the information society.
Dmytro Slobodianiuk
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Multi-level governance, governance roles and institutional entrepreneurship in public policies
The hypothesis advanced in the paper is that the effectiveness of multi-level governance in achieving given policy-objectives in a given context depends on the performance of the individuals who, being in a boundary position, connect the different levels
DE VIVO, PAOLA, Cerase F. P., Sacco E.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

