Results 101 to 110 of about 31,819,981 (309)

Evaluation of digital development of administrative and territorial units of Dnipropetrovsk region

open access: yesAspekti Publìčnogo Upravlìnnâ, 2019
The article presents and analyzes the results of the May 2019 study of the digital development of districts, cities and territorial communities of Dnipropetrovsk region. It is through such research that we can identify critical territories, local digital
Sergiy Kvitka   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

China Joins Global Health Governance: New Player, More Medicines, and New Rules? [PDF]

open access: yes, 2014
In the wake of China’s rapid ascendancy, are there any new rules made by the country in global health governance? This paper examines China’s emerging role in the Agreement on Trade-Related Aspects of Intellectual Property Rights, and finds that China ...
Lee, Pak K.   +3 more
core   +1 more source

GLASS: A Citizen-Centric Distributed Data-Sharing Model within an e-Governance Architecture. [PDF]

open access: yesSensors (Basel), 2022
Lo O   +5 more
europepmc   +1 more source

GOVERNANCE OF E-COMMERCE TECHNOLOGY DOWNSTREAMING IN EMPOWERING MICRO, SMALL, AND MEDIUM ENTERPRISES (MSMES) IN TRADITIONAL CULINARY BUSINESSES

open access: yesEksis: Jurnal Riset Ekonomi dan Bisnis
This study analyzes the implementation of technology downstream governance in e-commerce for empowering traditional culinary MSMEs in Soppeng Regency, South Sulawesi.
Zulfachry Zulfachry   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Ineffectiveness of the Smart City Program in the Demographic Field (Study on the Use of E-SIAP in Disepndukcapil Blitar Regency)

open access: yesWacana: Jurnal Sosial dan Humaniora, 2020
Smart city is a program that has been implemented by various countries, including Indonesia. The application in different countries is also different. In other words, this program is adjusted to the capabilities of each country and citizens. This program
Rosy Nursita Anggraini   +2 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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