Results 121 to 130 of about 34,125,650 (293)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Predictors for E-Government Adoption of SANAD App Services Integrating UTAUT, TPB, TAM, Trust, and Perceived Risk. [PDF]

Int J Environ Res Public Health, 2022
AlHadid I, Abu-Taieh E, Alkhawaldeh RS, Khwaldeh S, Masa'deh R, Kaabneh K, Alrowwad A.   +6 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

ANALISIS IMPLEMENTASI E-GOVERNMENT PADA PEMERINTAH DAERAH TINGKAT PROVINSI DI INDONESIA [ANALYSIS OF THE IMPLEMENTATION OF E-GOVERNMENT ON REGIONAL GOVERNMENT LEVEL IN INDONESIA]

, 2012
Sejak dikeluarkan Inpres Nomor 3/2003, setiap Kementerian, Non Kementerian, Provinsi, dan Kabupaten/Kotamadya telah mengimplementasikan dan mengembangkan e-Government.
Igif G Prihanto
core  

Effectiveness of using e-government platform "Absher" as a tool for noncommunicable diseases survey in Saudi Arabia 2019-2020: A cross-sectional study. [PDF]

Front Public Health, 2022
Alluhidan M, Alsukait RF, Alghaith T, Saber R, Alamri A, Al-Muhsen S, Alhowaitan F, Alqarni A, Herbst CH, Alazemi N, Hersi AS.   +10 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Northern Territory Government gazette : no. G38

, 1998
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.

core  

Government influence on e-government adoption by citizens in Colombia: Empirical evidence in a Latin American context. [PDF]

PLoS One, 2022
Ramirez-Madrid JP, Escobar-Sierra M, Lans-Vargas I, Montes Hincapie JM.   +3 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Northern Territory Government gazette : no. G19

, 2017
Made available via the Publications (Legal Deposit) Act 2004 (NT).This publication contains may contain links to external sites.

core