Results 41 to 50 of about 123,887 (261)
Social Sciences and Humanities OpenThe European Union faces the dual challenges of an ageing population and the rapid digital transformation of public services through e-government.
Emanuela Sala, Ekaterina Kochergina
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Digital Divide Measurement in Lembata Regency Using SIBIS
E3S Web of Conferences, 2018 Along with technological development in Indonesia, digital divide occurs in various regions, which were behind in terms of information on how to use, access and utilize ICT in collecting information from internet. One of the regions is Lembata Regency in
Dai Payon Binti Gabriel Cecilia +2 more
doaj +1 more source
Central European Public Administration Review, 2022 Purpose: Digitalization has been the driving change in creating jobs and increasing economic growth in recent years. However, the digitalization of countries and sectors is uneven. The paper focuses on various factors that have an impact on the economic
Armenia Androniceanu +2 more
doaj +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
An e-government adoption framework for developing countries: a case study from Sudan [PDF]
, 2012 Over the past decade, rapid progress in ICT has encouraged many governments to incorporate new technology into their national economic development strategies.
Abdalla, Sara
core
E-Government Development: Catalysing Agile Governance Transformation in Indonesia
Journal of Contemporary Governance and Public PolicyE-government is considered a crucial instrument for service transformation as it is believed to assist in achieving the government’s objectives by functioning as a flexible digital service platform for development.
Dyah Mutiarin +3 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Digital Government in Developing Countries: Reflections on the Korean Experience
, 2016 Chronicles the trend of information technology (IT) in its application to the challenges of public administration and effective service delivery and offers the Republic of Korea’s experience to demonstrate the broad stages of e-governance evolution ...
Choi, Chang Yong +5 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source