Results 41 to 50 of about 67,077,240 (222)

The impact of socio-economic and political factors on the development of e-government in developed and developing countries [PDF]

Problems and Perspectives in Management
Type of the article: Research Article Abstract The current direction of state development is its focus on citizens (G2C). This transition is accompanied by digitalization, which enables the provision of services to citizens to reach a whole new level ...
Alibek Samarkhanov, Gulsara Junusbekova, Zhaxat Kenzhin, Daulet Yesmagambetov   +3 more
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Institutional Trust and Governance Effectiveness as Mediators in Transforming Digital Maturity into Post-War Infrastructure Recovery [PDF]

Business Ethics and Leadership
The post-war recovery of Ukraine’s economy is accompanied by profound institutional transformations that require effective public governance mechanisms capable of ensuring infrastructure reconstruction, improving government effectiveness, and ...
Roman TOPAZLY, Roman STADNIICHUK, Larysa LIUBOKHYNETS, Nataliia SHUPRUDKO, Hanna ZHOSAN, Mykhailo PLIETNOV   +5 more
doaj   +1 more source

Government report: Digital Compass

, 2022
For the purpose of directing and managing the development of the digital transformation in Finland, a Digital Compass was drawn up. The work was steered by the ministerial working group on developing the digital transformation, the data economy and ...

core  

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

E-Government Development: Catalysing Agile Governance Transformation in Indonesia

Journal of Contemporary Governance and Public Policy
E-government is considered a crucial instrument for service transformation as it is believed to assist in achieving the government’s objectives by functioning as a flexible digital service platform for development.
Dyah Mutiarin, Nur Khaerah, Andi Visca Irfa Nyssa, Nasrulhaq Nasrulhaq   +3 more
doaj   +1 more source

Digital Government and the Circular Economy: Towards an Analytical Framework

, 2022
Circular economy is high on the political agenda, with governments at all levels setting ambitious goals to move away from traditional linear production models, where goods are used and disposed as waste, towards a future with less use of virgin raw ...
Tan, Y. (author), Rukanova, B.D. (author), Medaglia, Rony (author)   +2 more
core   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Digital Divide Measurement in Lembata Regency Using SIBIS

E3S Web of Conferences, 2018
Along with technological development in Indonesia, digital divide occurs in various regions, which were behind in terms of information on how to use, access and utilize ICT in collecting information from internet. One of the regions is Lembata Regency in
Dai Payon Binti Gabriel Cecilia, Budiyanto Setyohadi Djoko, Suyoto   +2 more
doaj   +1 more source