Results 21 to 30 of about 67,077,240 (222)

THE INSTITUTIONAL APPROACH TO MANAGEMENT OF THE QUALITY OF PUBLIC SERVICES IN THE E-GOVERNMENT 5.0 SYSTEM [PDF]

open access: yesProceedings on Engineering Sciences
This work elaborates on the evolution of public services as the key tool for implementing public policy in the conditions of digital transformation. The focus is on the transition from classical bureaucratic models to flexible digital approaches, such as
Bektur S. Raimberdiev   +3 more
doaj   +1 more source

Institutional foundations of digital transformation of business in economic sectors

open access: yesВестник университета, 2023
The article examines the external prerequisites for the digital transformation of business in the Russian economy. The object of research is the institutional infrastructure of the digital economy. The subject of the study is the state digital ecosystem.
P. M. Gureev, I. S. Prokhorova
doaj   +1 more source

Comparative analysis of E-government development status of ASEAN member states: Accomplishments and challenges

open access: yesSustainable Futures
E-government enhances efficiency, transparency, participation, and democracy through technology. Recent decades have seen global advancements in E-government, especially in the Asia-Pacific region. This study assesses E-government development of 10 ASEAN
Kittipong Tissayakorn
doaj   +1 more source

Silver surfers, e-government and the digital divide: An exploratory study of UK local authority websites and older citizens [PDF]

open access: yes, 2013
This is a pre-copyedited, author-produced PDF of an article accepted for publication in Interacting with Computers following peer review. The definitive publisher-authenticated version is available online at the link below.Governments around the globe ...
Ghinea, G.   +5 more
core   +1 more source

E-Government Development Index (EGDI) and its relationship with the economic development level in the EAEU countries

open access: yesВестник университета, 2022
Modern digital technologies have become an important factor in improving the quality of public administration in the services provision by government bodies and structures and in ensuring sustainable development and economic growth.
O. V. Azoeva   +2 more
doaj   +1 more source

Benchmarking E-Government: Global Trends and Digital Divide

open access: yesСтатистика України
E-Government, being a basic component in the public administration, is a crucial factor in setting up information communications between various branches of the state power and in ensuring access of community and business to public services in online ...
А. М. Yerina
doaj   +1 more source

Advancing Australia as a digital economy: an update to the national digital economy strategy [PDF]

open access: yes, 2013
The Government’s 2011 National Digital Economy Strategy (the 2011 NDES) set the goal of Australia becoming a leading digital economy by 2020. In doing so, it nominated eight goals to position Australia as a world leader in broadband connectivity and the ...

core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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