Results 241 to 250 of about 180,067 (306)

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

What is the effect of commercial food and non-alcoholic beverage marketing on the dietary intake of children and adolescents? Protocol for systematic review and meta-analysis with an equity lens. [PDF]

Syst Rev
Chen QJ, Mozaffari H, Ananthapavan J, Smith BT, Wong GWK, Jessri M.   +5 more
europepmc   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

Cooperation mode selection and information sharing in a live streaming e-commerce supply chain with traffic data investment. [PDF]

PLoS One
Wang H, Zhu A, Yu L, Mu D, Meng Z.
europepmc   +1 more source

Cationic mRNA Lipid Nanoparticles for Ex Vivo NanoCAR‐T Cell Engineering

Advanced Science, EarlyView.
This study compares charge‑neutral and cationic lipidnanoparticles (LNPs) for ex vivo mRNA delivery to T cells, revealing distinctdependencies on medium composition and T cell activation. Where conventional LNPs benefit from ApoE‐dependent T cell targeting, cationic DOTAP‑modified LNPs mediate unspecific charge‑dependent transfection.
Laure Harinck, Stijn De Munter, Margo De Velder, Joline Ingels, Dominika Berdecka, Ine Lentacker, Winnok H. De Vos, Bart Vandekerckhove, Kevin Braeckmans, Koen Raemdonck   +9 more
wiley   +1 more source

#notforkids: alcohol, vaping, and cannabis marketing by social media influencers popular with children and adolescents on YouTube, Instagram, and TikTok and policy implications. [PDF]

Arch Public Health
Potvin Kent M, Bagnato M, Pritchard M, Amson A, Remedios L, Sabir S, Gillis G, Pauzé E, Vergeer L, Vanderlee L, White CM, Hammond D.   +11 more
europepmc   +1 more source

Purchases of toddler formula in the USA: 17 years of household demographics and spending. [PDF]

Public Health Nutr
Kaidbey JH, Kuttamperoor JT, Sharkey AL, Dowling EA, Conigliaro T, Sylvetsky AC.   +5 more
europepmc   +1 more source

Marketing for Sensa: a 'zero nicotine vapor product' from a major tobacco company. [PDF]

Tob Control
Robichaud MO, Talbot EM, Ganz O, Mercincavage M, Erythropel HC, Zimmerman JB, Jabba SV, Jordt SE, Delnevo CD.   +8 more
europepmc   +1 more source

Health System Community Partnership to Design an Online Resource to Address Perinatal Information Needs for Black Families: Action Research Study. [PDF]

JMIR Pediatr Parent
Taylor YJ, Dahl A, Isreal M, Spinner C, Sammons L, Fesperman D, Washington R, Mehta S, Howell C, Stamp J, Bundy H, Cobb P, Bridges Community Partner Group.   +12 more
europepmc   +1 more source

A Statistical Concept for Conditional Marketing Authorisation Based on the Intermediate and Final Outcomes of a Single Confirmatory Randomised Clinical Trial. [PDF]

Pharm Stat
Liu X, Thomas NH, Asikanius E, Pothet C, Großhennig A, Koch A.   +5 more
europepmc   +1 more source