Results 201 to 210 of about 435,103 (334)

Author Correction: Foundation model of neural activity predicts response to new stimulus types. [PDF]

Nature
Wang EY, Fahey PG, Ding Z, Papadopoulos S, Ponder K, Weis MA, Chang A, Muhammad T, Patel S, Ding Z, Tran D, Fu J, Schneider-Mizell CM, MICrONS Consortium, Reid RC, Collman F, da Costa NM, Franke K, Ecker AS, Reimer J, Pitkow X, Sinz FH, Tolias AS.   +22 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

RTAS-Net: A ResNet-transformer-ASPP semantic segmentation network for remote sensing images. [PDF]

PLoS One
Wang Z, Li Y, Ma K.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

A conserved monocyte activation program links brain injury to systemic immune adaptation and clinical outcomes. [PDF]

Front Immunol
Sadek A, Petrier M, Fourgeux C, Braud M, Gourain V, Bouras M, Poulain C, Moumni M, Roquilly A, Poschmann J.   +9 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Identification and clinical implications of immune-related hub genes in psoriasis. [PDF]

PLoS One
Sun Y, Zhou Z, Mao Y, Liu N, Li Y, Fang W.   +5 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Ingestible active capsule for gastrointestinal microbiome sampling. [PDF]

Biomed Microdevices
Shahadha MH, Voigt A, Gruner D, Marschner U, Le Floch M, Hampe J, Brauer F, Schostek S, Luniak M, Bock K, Richter A.   +10 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source