Results 161 to 170 of about 33,283,713 (295)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Improved visualization of malpositioned middle ear prostheses using photon-counting detector CT: a cadaver study. [PDF]

Radiol Adv
Sadeghian M, Benson JC, Farnsworth PJ, Lane JI, Treb KJ, Khandalavala KR, Babajanian EE, Bruesewitz MR, Swicklik JR, Ou FS, McCollough CH, Carlson ML, Leng S.   +12 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Diagnostic performance of clinical photon-counting CT in the assessment of peri-implantitis - an ex vivo diagnostic accuracy study. [PDF]

Int J Implant Dent
Ruetters M, Mertens C, Felten A, Blagoev B, Spies AN, Kim TS, Schlemmer HP, Schoenberg S, Froelich M, Kachelrieß M, Sawall S.   +10 more
europepmc   +1 more source

My kundalini website on e-reader

This book is a brainchild of the explorers while making the website “demystifyingkundalini.com” The website creator began to suspect that if the website went bad due to any reason unfortunately, then all the hard work would be spoiled, and all the text written would be gone.
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

An Assessment of PI-RADS v2.1: Inter-Reader Agreement, Diagnostic Accuracy, and the Added Value of PSA Density in Prostate Cancer Prediction. [PDF]

Diagnostics (Basel)
Abufaraj M, Al-Qalalweh SB, Kreishan AS, Abbadi RM, Ismail O, Labib A, Abu Shattal M, Bawi DA, Samara O, Alhanbali YE, Farah SN, Al-Abbadi MA, Shariat SF.   +12 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

The MOBCART (magnetic resonance observation of bone and cartilage repair tissue) add-on score. [PDF]

Insights Imaging
Koenig FRM, Schreiner M, Szomolanyi P, Juras V, Raudner M, Sorgo P, Wollner G, Filardo G, Winalski CS, Guermazi A, Bugbee WD, Trattnig S.   +11 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source