Results 171 to 180 of about 696,921 (266)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Erratum: [Corrigendum] TBL1XR1 as a potential therapeutic target that promotes epithelial-mesenchymal transition in lung squamous cell carcinoma. [PDF]

Exp Ther Med
Zhao Y, Lin H, Jiang J, Ge M, Liang X.
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

[Expression of Concern] Demethylation of microRNA-142 induced by demethylation agents plays a suppressive role in osteosarcoma cells. [PDF]

Oncol Lett
Ding M, Hu J, Ni J, Zheng Z, Song D, Wang J.   +5 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Impact of reader experience on the time-saving potential of a novel computer-aided tool for Ann Arbor staging of pediatric hodgkin lymphoma. [PDF]

Front Nucl Med
Vasyliv I, Barrow MJ, Baratto L, Kim HG, von Krüchten VR, Lokesha YU, Sarrami AH, Moeremans M, Guja KE, Hawk KE, Daldrup-Link HE.   +10 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

High performance of low-dose ultrahigh-resolution photon-counting detector CT for sacroiliac joint assessment in axial spondyloarthritis. [PDF]

Eur J Radiol Open
Wang H, Chen L, Wei G, Huang Y, Zhou Z, Dong H, Chang R, Xu Z, Wu J, Yu A, Zeng D, Li J, Wang Y, Du L, Yan F, Ye J, Lu Y, Qin L.   +17 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Chronic nitric oxide mediates dual-layer gene regulation through mRNA m⁶A positional remodeling and parallel transcriptional reprogramming. [PDF]

Redox Biol
Shayan S, Petraitis Kuschman H, Kevil CG, Thomas DD.   +3 more
europepmc   +1 more source