Results 61 to 70 of about 22,195,093 (313)

Resultados de la implementación de un programa piloto de optimización de antimicrobianos (PROA) en Atención Primaria

open access: yesAnales del Sistema Sanitario de Navarra, 2020
Fundamento. El objetivo de este estudio fue evaluar la implementación de un programa piloto de optimización de antimicrobianos (PROA) en equipos de Atención Primaria (EAP) en Navarra. Material y métodos.
N. Alzueta Isturiz   +5 more
doaj   +1 more source

Cost-effectiveness analysis of a strategy to delay progression to dialysis and death among chronic kidney disease patients in Lima, Peru

open access: yesCost Effectiveness and Resource Allocation, 2021
Background The Renal Health Program (RHP) was implemented in 2013 as a secondary prevention strategy to reduce the incidence of patients initiating dialysis and overall mortality.
E. M. Saldarriaga   +3 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Vol. 25, nº 09.Vigilancia de la Salud. Vigilancia de enfermedades no transmisibles EVOLUCION DE LA SALUD MENTAL EN ANDALUCÍA

open access: yes, 2020
Contiene el 'Exceso de casos por distrito' de la semana nn/2020, los 'Casos observados VS Esperados de Andalucía' entre las semanas nn/2020 y nn/2020 y el informe de la 'Gripe' de la semana nn/2020.
Servicio de Vigilancia y Salud Laboral
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Declaración de las Bibliotecas Virtuales de Salud ante la crisis de la COVID-19 [PDF]

open access: yes, 2020
La situación producida por la COVID-19 ha confirmado el papel de las bibliotecas del sistema sanitario y de investigación en salud como apoyo fundamental a los sanitarios e investigadores de ciencias de la salud en el acceso a la información científica ...
Instituto de Salud Carlos III. Biblioteca Nacional de Ciencias de la Salud
core  

Diagnostic Tools for the Identification of Babesia sp. in Persistently Infected Cattle

open access: yesPathogens, 2019
Bovine babesiosis is a tick-borne disease of cattle caused by the protozoan parasites of the genus Babesia. Babesia bovis, Babesia bigemina and Babesia divergens are considered by International health authorities (OIE) as the principal species of Babesia
J. Antonio Alvarez   +2 more
doaj   +1 more source

E-Salud: el desarrollo de la e-Salud en China

open access: yes, 2022
El sector de la salud electrónica tiene un futuro muy prometedor y un enorme mercado de aplicaciones, especialmente en China. China tiene una gran base de población, lo que supone una enorme base de usuarios potenciales para la industria. Con grandes catástrofes como la de COVID-19, el entorno social de China ha mostrado una buena cohesión y existe un ...
openaire   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

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