Results 101 to 110 of about 35,733,896 (313)

Lung Cancer: A Classic Example of Tumor Escape and Progression While Providing Opportunities for Immunological Intervention

Clinical and Developmental Immunology, 2012
Lung cancers remain one of the most common and deadly cancers in the world today (12.5% of newly diagnosed cancers) despite current advances in chemo- and radiation therapies. Often, by the time these tumors are diagnosed, they have already metastasized.
Martin R. Jadus, Josephine Natividad, Anthony Mai, Yi Ouyang, Nils Lambrecht, Sandor Szabo, Lisheng Ge, Neil Hoa, Maria G. Dacosta-Iyer   +8 more
doaj   +1 more source

E-services evaluation criteria: the case of Azerbaijan

Informacijos Mokslai, 2018
[full article in English] The development of evaluation and effective public administration mechanisms are crucial for providing effective e-government services. The article explores the international expertise in the field of the e-service evaluation
Farhad Yusifov, Aynur Gurbanli
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Plant disease and insect advisory, vol. 04, no. 14

, 2005
This publication, formally known as the Plant Disease and Insect Advisory newsletter by the Oklahoma Cooperative Extension Service, underwent a title transition.
Royer, Tom A., Sutherland, Al, Mulder, Phil   +2 more
core  

Teaching Social Marketing Using E-Service Learning Amidst Health and Humanitarian Crises: A Case Study from Lebanon. [PDF]

Int J Environ Res Public Health, 2022
Bardus M, Nasser AlDeen K, Kabakian-Khasholian T, Kanj M, Germani A.   +4 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Plant disease and insect advisory, vol. 03, no. 07: Wheat streak mosaic virus prevalent in western Oklahoma and the panhandle

, 2004
This publication, formally known as the Plant Disease and Insect Advisory newsletter by the Oklahoma Cooperative Extension Service, underwent a title transition.
Hunger, Bob
core  

Evaluation of Electronic Service-Learning (e-Service-Learning) Projects in Mainland China under COVID-19. [PDF]

Appl Res Qual Life, 2022
Shek DTL, Li X, Yu L, Lin L, Chen Y.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Plant disease and insect advisory, vol. 06, no. 11: Onion disease and crop development update

, 2007
This publication, formally known as the Plant Disease and Insect Advisory newsletter by the Oklahoma Cooperative Extension Service, underwent a title transition.
Shrefler, Jim
core