Results 121 to 130 of about 35,733,896 (313)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Paediatric dental A&E service during the COVID-19 pandemic in the Greater London area. [PDF]
Eur Arch Paediatr Dent, 2021 Patel N +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Plant disease and insect advisory, vol. 06, no. 21: Soybean rust alert [PDF]
, 2007 This publication, formally known as the Plant Disease and Insect Advisory newsletter by the Oklahoma Cooperative Extension Service, underwent a title transition.
Damicone, John
core
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Plant disease and insect advisory, vol. 02, no. 09: Wheat disease update - Oklahoma - 22 Apr, 2003
, 2003 This publication, formally known as the Plant Disease and Insect Advisory newsletter by the Oklahoma Cooperative Extension Service, underwent a title transition.
Hunger, Bob
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
, 2005 This publication, formally known as the Plant Disease and Insect Advisory newsletter by the Oklahoma Cooperative Extension Service, underwent a title transition.
Hunger, Bob
core
Comprehensive echocardiographic and biomarker assessment of patients with diabetic ketoacidosis
Cardiovascular DiabetologyBackground Systemic stress, inflammation, and hydroelectrolytic and acid‒base abnormalities observed during diabetic ketoacidosis (DKA) can cause changes in the heart and even induce cardiovascular damage.
Edgar Francisco Carrizales-Sepúlveda +4 more
doaj +1 more source