Results 61 to 70 of about 24,931,249 (311)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Department of Health and Community Services : Professional stream recruitment and retention project - final report

, 2002
Department of Health and Community Services : Professional stream recruitment and retention ...
Hancock, C, Strategic Workforce Services
core   +1 more source

Known unknowns: indirect energy effects of information and communication technology

Environmental Research Letters, 2016
Background. There has been sustained and growing interest in characterizing the net energy impact of information and communication technology (ICT), which results from indirect effects offsetting (or amplifying) the energy directly consumed by ICT ...
Nathaniel C Horner, Arman Shehabi, Inês L Azevedo   +2 more
doaj   +1 more source

Rozwój prosumpcji na rynku E-usług w Polsce

Polityki Europejskie, Finanse i Marketing, 2019
W dobie społeczeństwa informacyjnego wzrost zachowań prosumenckich nie byłby możliwy bez rozwoju technologii ICT. Interaktywność współczesnych mediów sprzyja rozwojowi zjawiska prosumpcji. Artykuł przedstawia zagadnienia związane z postępowaniem nabywców
Robert Wolny
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Case studies and sustainability modelling presented by cloud computing business framework [PDF]

, 2011
Cloud Computing Business Framework (CCBF) is proposed to help organisations achieve good Cloud design, deployment, migration and services. While organisations adopt Cloud Computing for Web Services, technical and business challenges emerge and one of ...
De Roure, David, Walters, Robert John, Wills, G, Walters, Robert, Chang, Victor, Chang, V, Wills, Gary, Walters, RJ, Roure, DD   +8 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Assessment of E-services and their Systems

Engineering Economics, 2010
Modern economy is shifting from goods to services. Together with rapid expansion of the information economy and electronic networks it converges in the concept of eservice. Public administrations like any other organizations or individuals can provide electronic services using modern information and communication technologies. A primary goal for public
Ostašius, Egidijus, Petravičiūtė, Živilė   +1 more
openaire   +2 more sources