Results 111 to 120 of about 39,369 (255)
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen +7 more
wiley +1 more source
In the present investigation the bacteriocin production of Enterococcus faecium 7C5 was tested during Taleggio cheesemaking. Results indicated that bacteriocin was produced in cheese and was stable until the end of ripening.
Neviani E. +3 more
core +1 more source
Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
wiley +1 more source
Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa
Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley +1 more source
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley +1 more source
Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham +11 more
wiley +2 more sources
Investigation of Recombinant SagA Antigen as A Potential Vaccine Candidate Against Enterococcus faecium Infection [PDF]
Objectives: Enterococcus faecium is a Gram-positive bacterium with evolving multi-drug resistance. It is one of the primary causes of urinary tract infections and endocarditis, among other opportunistic bacteria.
Roaa Elsayed +3 more
doaj +1 more source
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
The role of Enterococcal Surface Protein in the pathogenesis of Enterococcus faecium infections
In the last two decades Enterococcus faecium has emerged as a nosocomial pathogen. Successful treatment is increasingly hampered because of antibiotic resistance.
Heikens, E.
core
The protocol of a multi‐site, double‐blinded, clustered randomized controlled trial (cRCT) with a binary outcome of the presence of viable presumptive ESKAPEE pathogens on surfaces in and around hospital sinks is to be implemented in two Bolivian hospitals.
Lindsay B. Saber +14 more
wiley +1 more source

