The interaction of Helicobacter pylori with the adherent mucus gel layer secreted by polarized HT29-MTX-E12 cells. [PDF]
PLoS ONE, 2012 Helicobacter pylori colonises the gastric mucosa of humans. The majority of organisms live in mucus. These organisms are an important reservoir for infection of the underlying epithelium. Cell culture models for H.
Brendan Dolan +4 more
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Foods, 2022 Short chain fatty acids (SCFAs), especially butyrate (BUT), are known to promote intestinal health, but their role in the protection of intestinal barrier integrity is poorly characterized.
Carlotta Giromini +6 more
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PLoS ONE, 2021 The intestinal mucus layer plays a crucial role in human health. To study intestinal mucus function and structure in vitro, the mucus-producing intestinal cell line HT29-MTX-E12 has been commonly used. However, this cell line produces only low amounts of
Janneke Elzinga +3 more
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Protein inhibitor of activated STAT, PIASy regulates α-smooth muscle actin expression by interacting with E12 in mesangial cells. [PDF]
PLoS ONE, 2012 Phenotypic transformation of mesangial cells (MCs) is implicated in the development of glomerular disease; however, the mechanisms underlying their altered genetic program is still unclear.
Kazuo Torikoshi +12 more
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TWIST1 Heterodimerization with E12 Requires Coordinated Protein Phosphorylation to Regulate Periostin Expression [PDF]
Cancers, 2019 Diffuse invasion into adjacent brain matter by glioblastoma (GBM) is largely responsible for their dismal prognosis. Previously, we showed that the TWIST1 (TW) bHLH transcription factor and its regulated gene periostin (POSTN) promote invasive phenotypes
Svetlana A. Mikheeva +11 more
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Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci [PDF]
Journal of Experimental Medicine, 2009 The E2A gene products, E12 and E47, are critical regulators of B cell development. However, it remains elusive whether E12 and E47 have overlapping and/or distinct functions during B lymphopoiesis.
Kristina Beck +4 more
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A New Role for E12/E47 in the Repression ofE-cadherin Expression and Epithelial-Mesenchymal Transitions [PDF]
Journal of Biological Chemistry, 2001 Down-regulation ofE-cadherin expression is a determinant of tumor cell invasiveness, an event frequently associated with epithelial-mesenchymal transitions.
Mirna Pérez‐Moreno +6 more
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A new epoxy for plastination: feasibility and applicability analysis of the conservation of biological tissues [PDF]
Brazilian Journal of Medical and Biological ResearchPlastination is a technique for preserving biological tissues, in which body fluids are replaced by a curable polymer. Epoxy resin is used for 2-5 mm sections of anatomical segments, with the German-made Biodur® E12 being the best known and most widely ...
Y.F. Monteiro +5 more
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Study on yolk iron transportation in chick embryo eggs based on transcriptomics [PDF]
Poultry ScienceChick embryo eggs have a complete system of iron release, delivery, and uptake and thus provide a useful tool to study the fast transportation and absorption of iron.
Lulu Ma +5 more
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